Health and Medicine

August 12, 2016

New culprit in nerve degeneration

Vanderbilt researchers have discovered that regulation of cell volume plays a role in nerve degeneration and peripheral neuropathies.

By Leigh MacMillan
Richard Caprioli and mass spectrometer
August 11, 2016

NIH grant bolsters mass spectrometry research initiatives

The National Institutes of Health (NIH) has awarded a major renewal grant to continue the National Research Resource for Imaging Mass Spectrometry at Vanderbilt University School of Medicine.

By Bill Snyder
hand on radio tuning knob
August 11, 2016

Team explores transcription factor’s autoimmunity role

Increasing expression of a transcription factor called KLF2 can promote immunological self-tolerance and “tune down” autoimmunity, researchers at Vanderbilt University Medical Center reported recently.

By Bill Snyder
goofy toy disguise
August 11, 2016

Research team takes aim at Ebola virus ‘decoy protein’

Using an antibody generated at Vanderbilt University Medical Center that neutralizes the Ebola virus, researchers at the Scripps Research Institute in La Jolla, California, have determined the structure of a “decoy” protein that may enable the virus to evade detection by the immune system.

By Bill Snyder
August 11, 2016

Transcription factor evolution

Vanderbilt researchers have discovered a novel model of evolution for factors that control gene expression.

By Sanjay Mishra
Oxygen on periodic table
August 11, 2016

Study explores low oxygen’s impact on antibody quality

Hypoxia (lack of enough oxygen) is bad for the body as a whole, but in the neighborhood where infection-fighting antibodies arise, may be important for keeping proper order.

By Bill Snyder
August 11, 2016

Study reveals neurotransmitter glutamate’s molecular structure

Terunaga Nakagawa, with colleagues from Japan and Oxford University in England, has discovered the bridgelike molecular structure of a mysterious glutamate receptor.
By Bill Snyder
August 4, 2016

HIV treatment and TB risk

Tuberculosis (TB) remains an important public health problem, particularly among people infected with the human immunodeficiency virus (HIV).
By Bill Snyder
August 3, 2016

Kleberg Foundation grant bolsters cancer drug discovery efforts

The Robert J. Kleberg Jr. and Helen C. Kleberg Foundation has awarded a $3 million grant to Vanderbilt-Ingram Cancer Center (VICC) investigators in support of VICC’s drug discovery program. The gift awarded over the next three years from the private, San Antonio, Texas-based foundation will enable VICC researchers to pursue the development of new compounds to block the activity of cancer-causing genes and proteins that had previously been considered “undruggable.”
By VUMC News and Communications
August 3, 2016

Fetal impact of antidepressants

Antidepressant use during pregnancy is common. Fetal exposure to the class of antidepressants known as selective serotonin reuptake inhibitors (SSRIs) is associated with the life-threatening condition PPHN (persistent pulmonary hypertension of the newborn), but a causal link has not been established.
By Leigh MacMillan
August 2, 2016

Refining neural circuitry

During development, neural circuits are remodeled – some synapses are eliminated and others are strengthened – to produce a mature, functional nervous system.
By Leigh MacMillan
August 1, 2016

Possible overeating antidote

The 2C-subtype of the serotonin receptor (5HT2C), which binds the neurotransmitter serotonin, plays an important role in regulating food intake and metabolism.
By Bill Snyder
July 28, 2016

Award bolsters study of alcohol’s impact on the brain

Vanderbilt University researcher Danny Winder, Ph.D., has received a MERIT Award from the National Institute of Alcohol Abuse and Addiction (NIAAA), part of the National Institutes of Health, for his contributions to understanding how alcohol affects the brain.
By Bill Snyder
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