Research

Studies by Andrew Glazer, PhD, Giovanni Davogustto, MD, and colleagues found that genetic testing with information from electronic health records can reveal undiagnosed heart rhythm disorders.
April 28, 2022

Studies combine genetic testing, electronic health records to find undiagnosed diseases

Combining genetic testing with information from electronic health records revealed undiagnosed heart rhythm disorders and new conditions associated with inherited cancer gene mutations.

By Leigh MacMillan
April 26, 2022

Calculating risk for uterine fibroids

Vanderbilt researchers have constructed a polygenic risk score for uterine fibroids that will be useful for exploring causes of these benign tumors and identifying novel drug targets and therapies.

By Leigh MacMillan
April 25, 2022

Molecular testing across tumor types

The KRAS inhibitor sotorasib is newly approved for one kind of lung cancer; Vanderbilt researchers ask if it should be considered for another type if the tumor has the gene mutation it targets.

By Leigh MacMillan
April 21, 2022

When science spills onto social media

Vanderbilt researchers report that social media posts can offer insights into how the public feels about genome editing, with stances varying across platforms and differing from those of academics and policy makers.

By Paul Govern
April 21, 2022

Youthful healing for burn wounds

Topical treatment of burns with an immunosuppressive drug counteracted the negative effects of aging on wound healing, Vanderbilt researchers have discovered.

By Sarah E. Glass
April 20, 2022

Lehmann named to receive Vanderbilt Prize in Biomedical Science

Renowned developmental geneticist Ruth Lehmann, PhD, is the recipient of the 2022 Vanderbilt Prize in Biomedical Science.

By Bill Snyder
April 13, 2022

Additional COVID vaccine helps protect transplant patients

Additional booster doses of vaccine against COVID-19 are particularly important for those who are immunosuppressed, namely those who have had solid organ transplants, a new study shows.
By Nancy Humphrey
April 13, 2022

Study compares moral injury in health care workers and veterans

A study comparing 618 military veterans who deployed to a combat zone after Sept. 11, 2001, and 2,099 health care workers (HCWs) working during the COVID-19 pandemic found similar levels of potential moral injury (PMI), with 46.1% of veterans and 50.7% of HCWs reporting PMI.
By Emily Stembridge
April 13, 2022

Best way to place patients on breathing machines studied

Starting on April 4, Vanderbilt providers initiated the “Randomized Trial of Sedative Choice for Intubation” (RSI) study to determine whether ketamine or etomidate is better for preventing low blood pressure, low oxygen levels, serious heart problems, or even death for severely ill patients undergoing intubation.
By Kylie Avery
April 12, 2022

Financial impact of prior authorization

Prior authorization — health insurer approval of a medical intervention prior to treatment — costs more than $40 million for U.S. academic radiation oncology practices, with questionable value added to patient care.
By Leigh MacMillan
April 11, 2022

Peptides promote AFib arrhythmia

Peptide oligomers have detrimental metabolic effects and cause pro-arrhythmic electrophysiological changes in heart atria, suggesting they may contribute to atrial fibrillation.
By Leigh MacMillan
April 7, 2022

Computer eyeballs graft-vs-host disease

A machine learning algorithm identified areas of skin affected by chronic graft-versus-host disease on par with clinicians, opening the door to streamlining and standardizing this measure of patient response to therapy.
By Paul Govern
April 7, 2022

New prognosis predictor and target for gastric cancer

The protein CGA — a subunit of glycoprotein hormones — is a biomarker that predicts chemoresistance in gastric cancer and could be targeted along with EGFR to restore chemosensitivity.
By Sarah E. Glass
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