Research

March 18, 2021

Vanderbilt research played key role in new lung screen guidelines

The U.S. Preventive Services Task Force (USPSTF) has formally recommended two changes that will nearly double the number of people eligible for lung cancer screening by lowering the age from 55 to 50 and reducing the number of smoking history pack years from 30 to 20.

By Tom Wilemon
March 15, 2021

Artificial intelligence calculates suicide attempt risk at VUMC

A machine learning algorithm that predicts suicide attempt recently underwent a prospective trial at the institution where it was developed, Vanderbilt University Medical Center.

By Paul Govern
Contributors to the COVID-19 microbiome study include (front row, from left) Julie Bastarache, MD, Meghan Shilts, MS, MHS, (middle row, from left) Jodell Jackson, PhD, Suman Das, PhD, Angela Jones, MS, (back row, from left) Jonathan Schmitz, PhD, MD, Simon Mallal, MBBS, and Jordan Best, PhD.
March 11, 2021

‘Friendly’ bacteria may impact COVID severity

The U.S. Centers for Disease Control and Prevention (CDC) has awarded Vanderbilt University Medical Center a two-year, $3.7-million contract to determine genetic and bacterial factors that may increase the risk for severe illness and death from COVID-19.

By Bill Snyder
March 11, 2021

Electronic health record study discovers novel hormone deficiency

A novel hormone deficiency may exist in humans, Vanderbilt investigators have discovered. In an analysis of two decades worth of electronic health records, the researchers found that some patients have unexpectedly low levels of natriuretic peptide hormone in clinical situations that should cause high levels of the hormone.

By Leigh MacMillan
March 9, 2021

Markers for breast cancer progression

Vanderbilt researchers clarify how a microRNA associated with triple-negative breast cancer survival inhibits cancer progression, suggesting new treatment strategies.

By Sarah E. Glass
Danielle Buchanan, BS, right, and Daniel Claassen, MD, MS, are studying the relationship between clinical research coordinators principal investigators. (photo by Donn Jones)
March 8, 2021

Survey identifies factors in reducing clinical research coordinator turnover

Strong, collaborative relationships with principal investigators are a key factor of longevity in clinical research coordinator positions — an essential, but increasingly transient job in executing treatment-advancing clinical trials, Vanderbilt University Medical Center researchers found.

By Holly Fletcher
March 8, 2021

Temperature, newts and a skin-eating fungus

Salamanders are more sensitive to a skin-eating fungus at colder temperatures, pointing to locations of North America where pathogen invasion is most likely.
By Leigh MacMillan
March 4, 2021

Probiotic protection

A probiotic factor given early in life to mice prevented intestinal inflammation in adulthood, providing a rationale for probiotic intervention in individuals at high risk of developing inflammatory bowel disease.
By Anivarya Kumar
March 4, 2021

Monoclonal antibody “cocktail” blocks COVID-19 variants: study

A monoclonal antibody “cocktail” developed at Vanderbilt University Medical Center to neutralize the COVID-19 virus is effective against all known strains, or variants, of the virus, according to a report published today in the journal Nature Medicine.
By Bill Snyder
March 4, 2021

Targeting glucagon action in diabetes

Disrupting the action of glucagon — a pancreatic hormone that works to raise blood glucose — restores functional insulin-producing cells in mouse models of type 1 diabetes and may be a promising treatment strategy.
By Leigh MacMillan
March 4, 2021

Biostatistician DeMets set for next Discovery Lecture

David DeMets, PhD, known for his work on statistical methods to monitor interim clinical trial data for early evidence of benefit or harm, will deliver the next web-based Discovery Lecture.
By Leigh MacMillan
March 4, 2021

Chikungunya antibody identified at VUMC moves forward

Evotec, a drug company headquartered in Hamburg, Germany, has begun a phase 1 clinical trial of a monoclonal antibody against the chikungunya virus that was identified at Vanderbilt University Medical Center.
By Bill Snyder
February 25, 2021

Females with autism reach puberty earlier: study

Blythe Corbett, PhD, professor of Psychiatry and Behavioral Sciences and investigator with the Vanderbilt Kennedy Center, recently led a study which found that on average, females with autism spectrum disorder (ASD) experienced the onset of puberty 9.5 months earlier than their peers.
By Emily Stembridge
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