Research

Researchers from the Broad Institute of Harvard and MIT, the National Institutes of Health (NIH) and Vanderbilt University Medical Center for the first time have used a novel genome-editing technique to “rescue” mice from progeria, a rare genetic disease that causes accelerated aging.

Researchers at Vanderbilt University Medical Center and Case Western Reserve University in Cleveland have been awarded a five-year, $3.3 million grant by the National Cancer Institute to apply artificial intelligence (AI) to help customize treatment for oral cancer patients.

Michael Rosen, PhD, professor and chair of Biophysics at the University of Texas Southwestern Medical Center, will discuss mysterious cellular compartments known as “biomolecular condensates” during the next web-based Discovery Lecture.

Images of cells and tissues are a critical part of biomedical research as they show which molecules or proteins are present and where these molecules are located in the tissue. Using increasingly sophisticated microscopes and imaging approaches, scientists can now look at more than 40 different molecules at once, an approach known as multi-plex imaging, where in the past they could only look at three or four molecules at a time.

A team of Vanderbilt investigators has discovered that blocking a certain signaling pathway boosts antitumor immunity and reduces tumor growth and metastasis in models of breast cancer and melanoma.

This spring in the U.S., there were widespread delays in elective health care procedures and screenings. Hospitals, in observance of federal guidelines, were, for a time, conserving beds and protective equipment in preparation for a surge in COVID-19 admissions. And, perhaps on a more prolonged basis, patients in many areas of the country stayed away due to anxiety over catching COVID-19 from other patients or their health care team.