Aliquots

‘Proofreader’ key to coronavirus growth

A coronavirus protein is required for replication of the viral genome and may be a good treatment target for SARS and other diseases caused by coronaviruses.

Probing intestinal immune cell roles

A new in vitro system will allow investigators to explore how immune system T cells develop specialized functions.

Tumor factor spurs blood vessel growth

A newly identified factor regulates blood vessel growth in colorectal tumors and could be a promising target for cancer therapies.

Pregnancy promoter and protector

Alkaline phosphatase enzymes appear to play roles in promoting pregnancy and in protecting the uterus from bacterial infection.

Overcoming resistance in ovarian cancer

The nuclear receptor TR3 contributes to ovarian cancer cell death in response to platinum-based chemotherapy – and may be a good target for overcoming cell resistance to certain treatments.

Oxidative stress in autism

A biomarker for oxidative stress is elevated in patients with both autism spectrum disorder and gastrointestinal dysfunction, suggesting opportunities for individualized approaches to clinical care.

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