Aliquots

Vanderbilt researchers propose guidelines for defining patient retention in clinical studies – an important parameter that affects study conclusions and program evaluations.

Certain MRI metrics can be used to assess myelin loss in multiple sclerosis, which is important for planning and monitoring therapy.

A zebrafish model of a severe mitochondrial disease will be useful for developing new therapeutic approaches.

Glaucoma-causing mutations in the gene for myocilin reduce secretion of the protein into the aqueous humor, suggesting a new option for treatment.

Researchers are developing imaging methods to predict patient outcome early in the course of chemotherapy for breast cancer – to allow clinicians to adjust therapy for patients who are not responding.

A genetic variant that increases risk for atrial fibrillation also impacts the response to a common therapy for the heart rhythm disorder.

Diseases associated with mutations and changes in expression of the protein caveolin may result from faulty trafficking of the protein to the cell surface.