Aliquots

February 14, 2013

Cell connections key in valve disease

A protein that connects cells together participates in the calcification that occurs in heart valve disease.

By Leigh MacMillan
February 6, 2013

Linking oxygen, iron and red blood cells

The HIF oxygen-sensing pathway and its responses to low oxygen may be targeted for treatments of anemia and disorders of iron balance.

By Leigh MacMillan
February 4, 2013

Brain tumor TIP reveals new target

The protein TIP-1 appears to be a novel prognostic marker for glioblastoma and may be a good therapeutic target for disrupting tumor-driven blood vessel development.

By Leigh MacMillan
February 1, 2013

Cell source of heart’s blood vessels

An unexpected group of cells generates the coronary arteries and may be useful for regeneration therapies following injury to the heart.

By Leigh MacMillan
January 31, 2013

Do-it-yourself repair in the kidney

The kidney can mediate its own repair through proliferation of resident immune system cells.

By Leigh MacMillan
January 23, 2013

New view of DNA processing ‘hub’

Structural studies reveal a new framework for understanding a central player in DNA processing.

By Leigh MacMillan
January 21, 2013

HDL cholesterol impaired in kidney disease

HDL cholesterol is impaired in patients with chronic kidney disease – and may increase their cardiovascular disease risk.
By Leigh MacMillan
January 18, 2013

Seeing light receptor’s interactions

Understanding how the main receptor for light interacts with other signaling molecules may inform new pharmaceutical development.
By Leigh MacMillan
January 17, 2013

Zinc: a new antibiotic target?

It may be possible to fight hospital-acquired pathogens like Acinetobacter baumannii by targeting the bacterium’s need for the nutrient metal zinc.
By Leigh MacMillan
December 26, 2012

Preventing hardened heart valves

Blocking a serotonin receptor may provide a novel therapy for heart valve disease.
By Leigh MacMillan
December 24, 2012

A drug combo for ovarian cancer

Combining another drug with platinum-based chemotherapies may be more effective against ovarian cancer.
By Leigh MacMillan
December 21, 2012

Low prenatal alcohol’s brain impact

Even relatively low levels of in utero alcohol exposure impact fetal brain development, and the effects last into adulthood, study finds.
By VUMC News and Communications
December 20, 2012

Cancer markers from archived tissue

Archived tissue samples are yielding new disease biomarkers.
By VUMC News and Communications
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