American Diabetes Association

February 2, 2024

Study links small pancreas size to faster progression to stage 3 Type 1 diabetes

The study findings, published in the journal Diabetes Care, suggest that pancreas imaging can have a benefit in tracking disease development and recruitment for preventive and therapeutic trials.

By Jill Clendening
When half of their six children were diagnosed with what was then believed to be Type 1 diabetes, David and Ellen Pursell decided their family would participate in research related to the health condition. This family photo from several years ago includes, seated, from left, Peggy, Ramsey and Chrissy. Standing, from left, are Vaughan, Ellen, Martin, David and Parker.
March 9, 2023

Family’s participation key to advancing diabetes research

A study of one family from Alabama has led Vanderbilt researchers to discover that insulin deficiency, independent of the autoimmunity associated with Type 1 diabetes, is the principal factor leading to a markedly smaller pancreas.

By Jill Clendening
June 22, 2022

Gannon selected for American Diabetes Association Award

Maureen Gannon, PhD, professor of Medicine, Molecular Physiology and Biophysics, and Cell and Developmental Biology, is the recipient of the 2022 Lois Jovanovic Transformative Woman in Diabetes Award presented by the American Diabetes Association (ADA).

By Jill Clendening
Insulin in vials
November 11, 2021

New way to bEET insulin resistance

Signaling molecules called EETs could improve insulin resistance, a primary risk factor for Type 2 diabetes and cardiovascular disease, Vanderbilt researchers have discovered.

By Bill Snyder
September 7, 2021

Regulators of fat cell metabolism

Vanderbilt researchers have discovered new details of the regulation of fat cell metabolism, findings that are important for combating obesity.

By Leigh MacMillan
December 4, 2020

Researchers urge priority vaccination for individuals with diabetes due to increased COVID-19 impact

Vanderbilt University Medical Center researchers have discovered individuals with type 1 and type 2 diabetes infected with COVID-19 are three times more likely to have a severe illness or require hospitalization compared with people without diabetes.

By Jill Clendening
October 5, 2020

Clue to diabetic kidney disease

Vanderbilt researchers have identified a signaling pathway that promotes kidney fibrosis in patients with diabetes — and that could be targeted with an existing approved medication.
By Sarah E. Glass
July 25, 2019

Sex differences in kidney injury

Men are more susceptible to progressive kidney disease than women; new VUMC studies point to differences in the expression and activation of the EGF receptor.
By Kelsey Herbers
December 13, 2018

Lean vs. obese adipose tissue cells

A greater understanding of the mechanisms and cell types involved in returning adipose (fatty) tissue to the lean state may lead to more effective treatments for obesity.
By Bill Snyder
September 27, 2018

Fat tissue’s “iron sink”

Alyssa Hasty and colleagues demonstrated that immune cells called macrophages act in fat tissue to store iron and prevent iron toxicity.
By Sanjay Mishra
September 13, 2018

Healthy antibodies reverse diabetes

Vanderbilt researchers have discovered that IgM-type antibodies appear to play a protective role to prevent the development of type 1 diabetes — and that purified IgM antibodies can reverse the disease.
By Leigh MacMillan
August 16, 2018

YAP after acute kidney injury

Activation of the signaling protein YAP may be a target for treating acute kidney injury, which affects up to 20 percent of hospitalized patients.
By Sanjay Mishra
September 28, 2017

Cellular calcium handling in diabetes

Potassium channels in a cellular organelle regulate calcium flux and appear to play a critical role in pancreatic beta cell health.
By Leigh MacMillan
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