bacteria

March 23, 2023

E. coli uses serine to abide acidity

Vanderbilt researchers have discovered another acid resistance mechanism for UTI-causing E. coli, laying the foundation for targeted antibacterial therapies.

By Cherie Saffold
February 3, 2022

Team to study using probiotics to reduce heart disease risk

A Vanderbilt research team has received a $7 million grant from the National Institutes of Health (NIH) to understand how alcohol’s effect on the gut microbiome drives heart disease.

By Matt Batcheldor
September 10, 2021

Caught in a web: study reveals that immune cells cooperate to trap and kill bacteria

Vanderbilt researchers have identified a new antibacterial mechanism that could inspire novel strategies for combating staph and other extracellular bacterial pathogens.

By Leigh MacMillan
May 19, 2020

Probing innate immunity

Manuel Ascano team validates an inhibitor of the cGAS-STING signaling pathway, which is important for cellular innate immunity against bacteria, viruses, and our own damaged DNA.

By Leigh MacMillan
October 3, 2019

New test assists physicians with quicker treatment decisions for sepsis

Rapid blood culture diagnostics for patients with bacterial bloodstream infections delivered final results in 12 hours versus the two to three days required for conventional testing.

By Jessica Pasley
yogurt
August 8, 2019

A probiotic treatment for obesity?

Engineered bacteria that produce beneficial compounds — and that could potentially be administered in foods like yogurt — may be a future treatment for obesity and other chronic diseases.

By Leigh MacMillan
June 6, 2019

Mouth microbes and colorectal cancer

Microbial species in the mouth could be playing a role in colorectal cancer development, according to new research from epidemiologists at VUMC.
By Leigh MacMillan
April 11, 2019

How bugs overcome host defenses

Vanderbilt researchers led by Eric Skaar are probing the mechanisms bacteria use when faced with nutrient starvation — a host defense strategy called “nutritional immunity.”
By Leigh MacMillan
January 11, 2018

Lighting up iron levels

A new probe enables iron imaging in living animals, providing a unique tool for studying iron’s contributions to health and disease.
By Leigh MacMillan
April 19, 2017

Predicting the infection response

Vanderbilt investigators are probing the response to a bacterial toxin as a clinical assessment of immune function.
By Sanjay Mishra
February 3, 2017

Bacterial signaling systems

Vanderbilt researchers have identified a unique example of communication between bacterial signaling systems, which may have relevance for antibiotic resistance.
By Leigh MacMillan
February 11, 2016

Slight chemical change may improve TB treatments: study

One small chemical change to an existing antibacterial drug results in a compound that is more effective against its target enzyme in tuberculosis, Vanderbilt researchers have discovered.
By Leigh MacMillan
January 7, 2016

Immune tolerance in endothelial cells

Inducing “tolerance” to bacterial toxins in the endothelial cells that line blood vessels may offer a new approach for preventing the negative consequences of sepsis.
By Leigh MacMillan
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