Basic Sciences

Inflammation synergizes with a cell’s intrinsic genetic program to promote the development of pancreatic cancer.

Engineered bacteria that produce beneficial compounds — and that could potentially be administered in foods like yogurt — may be a future treatment for obesity and other chronic diseases.

A previously unrecognized role for a cell surface receptor may open new therapeutic options for the treatment of fibrotic diseases.

Microtubules — part of the cell's cytoskeleton — regulate the secretion of insulin, suggesting that they may be a new target for treating diabetes.

Investigators have discovered how a DNA repair pathway protein shields sites of damage to avoid mutations and maintain genome integrity.

A first-of-its-kind mouse model may help reveal mechanistic underpinnings for the altered behaviors of autism spectrum disorder.

Vanderbilt-Ingram Cancer Center scientists have discovered a role for a tumor suppressor protein in skin wound healing.