big data

Berlin Institute of Health’s Eils set for next Discovery Lecture

Roland Eils, PhD, will discuss efforts to translate the deluge of genomics data generated by international initiatives into understanding disease mechanisms during the next web-based Discovery Lecture.

New tool to probe genetic mechanisms of disease

Vanderbilt Genetics Institute investigators have added a new method to the computational genetics toolbox. Their approach, described in the journal Nature Genetics, integrates vast genomics datasets to predict gene expression and facilitate discovery of genetic mechanisms underlying human diseases.

Original podcast series explores ideas, issues shaping health and health care

Study merges big data and zebrafish biology to reveal mechanisms of human disease

In a series of studies that volleyed between large databases and research in zebrafish, Vanderbilt investigators have discovered a link between vascular biology and eye disease.

Predictive models for gene regulation

Using new computational approaches to understand the behavior of cells should aid efforts to predict how mutations affect cell function and how diseases respond to drug combinations.

Former FDA official explores big data’s impact on healthcare

“Big data” can help reverse the alarming decline in life expectancy in the United States — if universities and academic medical centers take the lead, former U.S. Food and Drug Administrator Robert Califf, MD, told a Vanderbilt audience last week.