cancer biology

x-ray of stomach
November 3, 2016

A DARPP role in gastric cancer

Vanderbilt researchers have discovered a link between Helicobacter pylori infection, inflammation and gastric cancer that could suggest new anti-cancer therapies.

By Sanjay Mishra
firefighters battle a wildfire
October 13, 2016

EGF receptor found to regulate macrophage inflammation in gut

Researchers at Vanderbilt University School of Medicine have uncovered a link between epidermal growth factor receptor (EGFR) signaling and the inflammatory response to bacterial infection in the gastrointestinal tract.

By Bill Snyder
October 6, 2016

Basic science, extraordinary impact

The discoveries that can change the course of human health forever often begin in the tiniest places: in molecules and cells, at the most fundamental intersection of physics, chemistry and biology. Understanding how these cellular and molecular processes work is the focus of basic biomedical research at Vanderbilt.

By Liz Entman and Melanie Moran
September 9, 2016

In search of new cancer targets

Vanderbilt researchers developed a new algorithm to find clinically targetable gene rearrangements in cancers.

By Leigh MacMillan
August 31, 2016

Proliferative capacity of neuroblastoma

The sphere-forming frequency of neuroblastoma cells is a measure of their proliferative capacity and could help guide treatment strategies for neuroblastoma.

By Sanjay Mishra
August 26, 2016

New breast cancer driver

Vanderbilt investigators have demonstrated that a certain protein complex drives tumor progression in aggressive breast cancers.

By Leigh MacMillan
June 22, 2016

Lovly tapped to brief Congress on cancer research

Christine Lovly, M.D., Ph.D., assistant professor of Medicine and Cancer Biology, has been selected to testify before members of Congress about the importance of cancer research, including early training programs for individuals interested in science.
By Doug Campbell
June 6, 2016

Pulmonary fibrosis culprits

New findings identify isoketal-modified proteins as a previously unrecognized feature of pulmonary fibrosis and as a potential therapeutic target for this disease.
By Leigh MacMillan
May 12, 2016

Thompson’s Discovery Lecture

Craig Thompson, M.D., president and CEO of Memorial Sloan Kettering Cancer Center, spoke about his lab’s research linking metabolism to stem cell maintenance during his recent Flexner Discovery Lecture.
By VUMC News and Communications
May 5, 2016

Current cancer drug discovery method flawed: VUMC study

The primary method used to test compounds for anti-cancer activity in cells is flawed, Vanderbilt University researchers reported May 2 in Nature Methods.
By Leigh MacMillan
May 3, 2016

Drug combos for glioblastoma

Vanderbilt researchers have discovered that activation of a certain signaling pathway protects brain cancers from targeted therapies, suggesting that using therapeutics that block both pathways may be a promising treatment.
By Leigh MacMillan
April 28, 2016

An Argonaute’s voyage to cancer

A genetic mutation that promotes cancer development blocks the normal sorting of a protein called “Argonaute 2.”
By Bill Snyder
April 28, 2016

Cancer expert Thompson to deliver May 5 Flexner Discovery Lecture

Craig Thompson, M.D., president and CEO of Memorial Sloan Kettering Cancer Center, will deliver the next Flexner Discovery Lecture on May 5.
By Leigh MacMillan
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