cancer biology

September 30, 2013

Gene interactions and cavities

Vanderbilt researchers used existing genome-wide association study datasets to identify gene interactions that contribute to tooth decay.

By Leigh MacMillan
August 26, 2013

Tumor factor spurs blood vessel growth

A newly identified factor regulates blood vessel growth in colorectal tumors and could be a promising target for cancer therapies.

By Leigh MacMillan
July 25, 2013

Visualizing data on network ‘maps’

The new web application NetGestalt will allow investigators to simultaneously visualize different types of data for the same gene – such as mutation, expression and modification.

By Leigh MacMillan
June 24, 2013

Predicting cancer’s response to therapy

Researchers are developing imaging methods to predict patient outcome early in the course of chemotherapy for breast cancer – to allow clinicians to adjust therapy for patients who are not responding.

By Leigh MacMillan
May 15, 2013

Inner ear’s role in bone remodeling

The inner ear system that senses gravity and movement plays a role in bone remodeling – a finding that has clinical implications for space travel and for patients with inner ear disorders.

By Leigh MacMillan
May 9, 2013

Dual-action enzyme protects esophagus

An antioxidant enzyme also functions as a tumor suppressor to limit cancer development in the esophagus.

By Leigh MacMillan
April 11, 2013

Leukemia culprit’s cellular actions

Overexpression of a gene that is a common culprit in leukemia induces stem cell-like features in T cells, which may enable the cells to become cancerous.
By Leigh MacMillan
April 4, 2013

Nobel laureate Hartwell set for Discovery Lecture

Nobel laureate Lee Hartwell, Ph.D., will deliver the next Flexner Discovery Lecture on Thursday, April 11.
By Leigh MacMillan
March 28, 2013

Foundation lauds graduate student’s melanoma research

Katherine Hutchinson, a third-year graduate student in Cancer Biology at Vanderbilt University, has won a $10,000 Research Scholar Award from the Joanna M. Nicolay Melanoma Foundation.
By Bill Snyder
March 20, 2013

New drugs a good BET for brain cancer

A novel class of drugs that target “BET” proteins may have broad utility for treating genetically diverse brain tumors.
By Leigh MacMillan
February 6, 2013

Linking oxygen, iron and red blood cells

The HIF oxygen-sensing pathway and its responses to low oxygen may be targeted for treatments of anemia and disorders of iron balance.
By Leigh MacMillan
February 4, 2013

Brain tumor TIP reveals new target

The protein TIP-1 appears to be a novel prognostic marker for glioblastoma and may be a good therapeutic target for disrupting tumor-driven blood vessel development.
By Leigh MacMillan
January 31, 2013

Do-it-yourself repair in the kidney

The kidney can mediate its own repair through proliferation of resident immune system cells.
By Leigh MacMillan