cancer

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November 18, 2021

Team receives Association of Community Cancer Centers Innovator Award

A team of Vanderbilt employees have received and award for implementing a streamlined follow-up protocol for patients who may not know they have cancer.

By Tom Wilemon
The team studying tumor suppressor protein p53 includes, from left, Jennifer Pietenpol, PhD, and Lindsay Redman-Rivera.
September 2, 2021

Discovery offers insight for development of cancer therapies targeting mutant p53

Vanderbilt researchers have discovered that aneuploidy (an abnormal number of chromosomes) drives malignant phenotypes in cells expressing mutant p53, a tumor suppressor protein that is mutated in more than half of all human cancers.

By Bill Snyder
August 19, 2021

Expression atlas for cell regulators

Vanderbilt researchers report a comprehensive tissue-specific atlas of protein and mRNA expression for p63 and p73, members of the p53 family signaling network that is the most frequent target of mutations in human cancers.

By Leigh MacMillan
July 27, 2021

Prediction models for breast cancer

Vanderbilt researchers developed new prognostic models for breast cancer outcomes and found that adding postdiagnostic weight change as a factor improves the prediction.

By Leigh MacMillan
Madison Adolph, PhD, left, David Cortez, PhD, and Archana Krishnamoorthy are studying fundamental processes involved in DNA replication.
July 22, 2021

Researchers discover that protein switches functions to regulate DNA replication

Vanderbilt biochemists have discovered what the DNA damage response protein RADX does — and how it does it.

By Leigh MacMillan
June 9, 2021

National Black Family Cancer Awareness Week is call to action

National Black Family Cancer Awareness Week, June 17-23, aims to spur conversations followed by actions to make advancements in care more equitable.

By Tom Wilemon
April 20, 2021

The inside story behind the Hillsboro Village “Hope” mural: a brother’s love and a message for Children’s Hospital

Lance Gregory wanted the message to be visible from the windows of Children's Hospital — in memory of his brother Cory
By Christina Echegaray
April 15, 2021

Method proposed to correct misinterpretations of long-term survival rates for immunotherapies

Immune checkpoint inhibitors have transformed cancer care to the point where the popular Cox proportional-hazards model provides misleading estimates of the treatment effect, according to a new study published April 15 in JAMA Oncology.
By Tom Wilemon
March 22, 2021

Chemo for cancer lowers dementia risk

Cancer chemotherapy lowered risk of Alzheimer’s disease and other neurocognitive disorders that disproportionately affect older people.
By Paul Govern
March 19, 2021

COVID-19 and Cancer Consortium study highlights racial disparities, increased mortality for patients facing dual diagnoses

The COVID-19 and Cancer Consortium (CCC19) published new findings in the Annals of Oncology showing heightened mortality and racial disparities for patients with cancer diagnosed with SARS-CoV-2 infection.
By VUMC News and Communications
January 21, 2021

WIN for blocking cancer growth

William Tansey and colleagues identified proteins that interact with the cancer drug target WDR5 and are important for cancer cell growth.
By Sarah E. Glass
January 7, 2021

Vitamin D activation and cancer risk

Vitamin D protection against colon cancer varies according to parathyroid hormone response, particularly among women.
By Paul Govern
October 26, 2020

Philadelphia Eagles pick VUMC resident to sing national anthem before game

The lifelong Eagles fan closed "The Star-Spangled Banner” with a big smile and the exhortation “Go, Birds!”
By Wayne Wood
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