A noninvasive MRI approach assesses breast tumor cell size and could be a useful way to evaluate early response to neoadjuvant therapy.

A newly identified protein interaction that affects cell cycle regulation may be an attractive target for cancer therapy.

Vanderbilt researchers have uncovered another piece in the puzzle of how cells divide — a process that goes awry in cancer cells.

Jason MacGurn and colleagues have characterized a “rheostat” that sets WNT pathway signaling in breast cancer cells.

Gene variants associated with cancer risk appear to contribute to carcinogenesis by regulating target genes that in turn promote the generation of mutations.

A previously unrecognized role for a cell surface receptor may open new therapeutic options for the treatment of fibrotic diseases.

Investigators have discovered how a DNA repair pathway protein shields sites of damage to avoid mutations and maintain genome integrity.