Three rows of tissue microscopy panels showing stained tissue sections alongside separate blue, green, and red fluorescence channels and merged overlays with outlined regions.
August 19, 2021

Expression atlas for cell regulators

Vanderbilt researchers report a comprehensive tissue-specific atlas of protein and mRNA expression for p63 and p73, members of the p53 family signaling network that is the most frequent target of mutations in human cancers.

Three smiling women in traditional-style clothing stand in a row before a dark red background with rows of gold decorative knobs.
July 27, 2021

Prediction models for breast cancer

Vanderbilt researchers developed new prognostic models for breast cancer outcomes and found that adding postdiagnostic weight change as a factor improves the prediction.

Madison Adolph, PhD, left, David Cortez, PhD, and Archana Krishnamoorthy are studying fundamental processes involved in DNA replication.
July 22, 2021

Researchers discover that protein switches functions to regulate DNA replication

Vanderbilt biochemists have discovered what the DNA damage response protein RADX does — and how it does it.

A bearded man stands in front of a brick-wall mural spelling “HOPE” in large yellow letters, with a yellow awareness ribbon replacing the “O.”
April 20, 2021

The inside story behind the Hillsboro Village “Hope” mural: a brother’s love and a message for Children’s Hospital

Lance Gregory wanted the message to be visible from the windows of Children’s Hospital — in memory of his brother Cory

VUMC NEWS logo in white lettering inside a cyan and yellow outlined square on a blue gradient background.
April 15, 2021

Method proposed to correct misinterpretations of long-term survival rates for immunotherapies

Immune checkpoint inhibitors have transformed cancer care to the point where the popular Cox proportional-hazards model provides misleading estimates of the treatment effect, according to a new study published April 15 in JAMA Oncology.

Stylized side-profile illustration of a human head with the skull rendered translucent to reveal a network resembling brain blood vessels, dissolving into particles against a peach background.
March 22, 2021

Chemo for cancer lowers dementia risk

Cancer chemotherapy lowered risk of Alzheimer’s disease and other neurocognitive disorders that disproportionately affect older people.