cell and developmental biology

March 7, 2016

A clue to cell cleavage

Actin and microtubule cytoskeletons are coordinated during cytokinesis – the process that separates one cell into two and is linked to events underlying cancer.

By Sanjay Mishra
February 10, 2016

Overcoming lung cancer drug resistance

Vanderbilt investigators have discovered a way to overcome the resistance of some lung cancers to certain targeted therapies, which could lead to more effective treatments for lung cancer patients.

By Marilyn Holt
February 8, 2016

Building intestinal brush borders

Studies of the molecular complex that helps build specialized cellular surfaces could shed light on the mechanisms underlying a genetic deaf-blindness syndrome accompanied by intestinal disease.

By Leigh MacMillan
egg cut in half
January 28, 2016

Findings offer new insight on how cell division proteins work

A family of proteins with critical roles in cell division, synaptic transmission and cell migration don’t all function the way scientists thought they did, according to two new studies led by Vanderbilt researchers.

By Leigh MacMillan
January 21, 2016

New targets for diabetic retinopathy

Certain protein factors have been identified as attractive targets for treating diabetic retinopathy, a major cause of blindness in adults.

By VUMC News and Communications
December 14, 2015

DISSECTing cell signaling networks

Vanderbilt researchers have developed a new method to study cell signaling networks at single-cell resolution.

By Leigh MacMillan
December 3, 2015

Microtubules act as cellular ‘rheostat’ to control insulin secretion

Microtubules — cellular “highways” that deliver cargo to the cell membrane for secretion — have a surprising role in pancreatic beta cells. Instead of facilitating glucose-stimulated insulin secretion, they limit it, a team of Vanderbilt investigators reported recently in Developmental Cell.
By Leigh MacMillan
October 29, 2015

Program gives undergrads from Peru lab experience

There’s a little bit of Peru in the Department of Cell and Developmental Biology.
By Bill Snyder
September 18, 2015

Nerve cell remodelers

Vanderbilt investigators have defined a gene expression program that controls the timing of synaptic remodeling – a process that is critical to brain development, learning and memory.
By Leigh MacMillan
September 17, 2015

Heart repair factor

A signaling factor called Wnt10b is a novel target for optimizing cardiac repair after a heart attack.
By Yan Su
September 3, 2015

Bad “traffic” linked to cancer

Understanding how signaling molecules are transported within and out of the cell may help to uncover the causes of certain cancers.
By VUMC News and Communications
August 20, 2015

New therapeutic target for diabetes

The factor FoxM1 increases the proliferation and function of insulin-producing beta cells, making it an attractive therapeutic target for diabetes.
By Leigh MacMillan
August 13, 2015

Macara lands award to explore cancer cell behavior

Vanderbilt’s Ian Macara, Ph.D., has won an Outstanding Investigator Award from the National Cancer Institute (NCI) — nearly $6.6 million over seven years — to support the “unusual potential” of his research, which seeks to understand and predict cancer cell “behavior.”
By Bill Snyder
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