cell and developmental biology

February 9, 2015

Gene profile predicts metastasis

A specific gene expression profile represents a novel, biologically relevant “signature” for identifying colon cancers with high risk of metastatic recurrence, Vanderbilt researchers have found.

By Yan Su
January 28, 2015

New clue to a devastating disease

New findings suggest a previously unrecognized role for the Sox10 transcription factor in Hirschsprung’s disease, and may lead to improved diagnostic and therapeutic approaches for this disease.

By Bill Snyder
November 24, 2014

Twelve Vanderbilt faculty elected AAAS fellows

Twelve members of Vanderbilt’s faculty have been elected fellows of the American Association for the Advancement of Science for their “scientifically or socially distinguished efforts to advance science or its applications.”

By Bill Snyder
October 30, 2014

VU study reveals factor’s new role in cell division, migration

Vanderbilt University investigators have discovered a new molecular mechanism that regulates microtubule dynamics. The unexpected finding, reported in Developmental Cell, has implications for cancer drug discovery.

By Leigh MacMillan
October 15, 2014

Antibiotics, fetal vessel defect linked

Certain antibiotics increase the risk of a congenital heart disorder called patency of the ductus arteriosis.

By VUMC News and Communications
October 9, 2014

Long-range signaling to stem cells

The potential for long-range signaling factors – such as those identified in the current study – to regulate stem cell behaviors has implications in tumor progression and metastasis.

By Leigh MacMillan
August 20, 2014

Study finds coronary arteries hold heart-regenerating cells

Endothelial cells residing in the coronary arteries can function as cardiac stem cells to produce new heart muscle tissue, Vanderbilt University investigators have discovered.
By Leigh MacMillan
May 29, 2014

Pioneers of Discovery: Investigator taps into artistic side to reveal cells’ secrets

Dylan Burnette, Ph.D., points to one of the many striking photographs on his office walls. It’s a picture of a cell — a microscopic image showing yellow squiggles, bright purple lines and a turquoise oval on a black background, and it looks like abstract art.
By Leigh MacMillan
April 30, 2014

Potential mechanism for myeloma drug’s variable toxicity

A genetic variant is associated with toxicity of the chemotherapy drug melphalan, and could guide individualized dosing for the medication.
By Leigh MacMillan
April 28, 2014

Prominent scientist, respected administrator Susan Wente named Vanderbilt provost and vice chancellor for academic affairs

After an extensive national search, Susan R. Wente has been named provost and vice chancellor for academic affairs, Chancellor Nicholas S. Zeppos announced today.
By VUMC News and Communications
April 17, 2014

Nutrient-absorbing surface’s assembly revealed: study

Vanderbilt University researchers have discovered how intestinal cells build the "brush border" -- a specialized surface structure that is critical for absorbing nutrients and defending against pathogens.
By Leigh MacMillan
April 2, 2014

Development and disease in the aorta

Smooth muscle cells that line the aorta differ in development but not in the adult, a finding that has implications for understanding aortic development and disease.
By Peng Xu
February 6, 2014

Discovery Lecture sheds light on properties of motion

Ron Vale, Ph.D., co-discoverer of the molecular “motor” kinesin, spent the first 10 minutes of his Flexner Discovery Lecture last week talking not about science, but about science communication.
By Bill Snyder
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