Department of Medicine

Allison Norlander, PhD, R. Stokes Peebles, MD, and colleagues are studying an approved drug that enhances immune cells and might be useful for treating inflammatory and autoimmune diseases.
March 25, 2021

Team studies new use for pulmonary hypertension drug

An FDA-approved medication enhances the function of T regulatory cells (Treg), a class of immune cells that restrains the immune response, Vanderbilt investigators have discovered.

By Leigh MacMillan
March 23, 2021

Prostate cancer microenvironment

Distinct cancer-associated fibroblasts in the prostate tumor microenvironment may influence tumor progression and could point to new therapeutic targets.

By Leigh MacMillan
March 19, 2021

COVID-19 and Cancer Consortium study highlights racial disparities, increased mortality for patients facing dual diagnoses

The COVID-19 and Cancer Consortium (CCC19) published new findings in the Annals of Oncology showing heightened mortality and racial disparities for patients with cancer diagnosed with SARS-CoV-2 infection.

By VUMC News and Communications
March 18, 2021

HIV, diabetes and immune cells in fat

In HIV-positive individuals with diabetes, immune cells in fat are more proinflammatory and cytotoxic and may represent a therapeutic target for diabetes.

By Leigh MacMillan
March 18, 2021

Vanderbilt research played key role in new lung screen guidelines

The U.S. Preventive Services Task Force (USPSTF) has formally recommended two changes that will nearly double the number of people eligible for lung cancer screening by lowering the age from 55 to 50 and reducing the number of smoking history pack years from 30 to 20.

By Tom Wilemon
March 18, 2021

Device to treat AFib may eliminate need for blood thinners

Vanderbilt University Medical Center is participating in a trial for a device that could revolutionize the way patients are treated for atrial fibrillation (AF or AFib.)

By Matt Batcheldor
March 18, 2021

EGFR Resisters/LUNGevity fund lung cancer research

Christine Lovly, MD, PhD, associate professor of Medicine in the Division of Hematology and Oncology and Ingram Professor of Cancer Research, is one of two inaugural recipients of the EGFR Resisters/LUNGevity Lung Cancer Research Award.
By Tom Wilemon
March 15, 2021

Artificial intelligence calculates suicide attempt risk at VUMC

A machine learning algorithm that predicts suicide attempt recently underwent a prospective trial at the institution where it was developed, Vanderbilt University Medical Center.
By Paul Govern
March 11, 2021

‘Friendly’ bacteria may impact COVID severity

The U.S. Centers for Disease Control and Prevention (CDC) has awarded Vanderbilt University Medical Center a two-year, $3.7-million contract to determine genetic and bacterial factors that may increase the risk for severe illness and death from COVID-19.
By Bill Snyder
March 11, 2021

Electronic health record study discovers novel hormone deficiency

A novel hormone deficiency may exist in humans, Vanderbilt investigators have discovered. In an analysis of two decades worth of electronic health records, the researchers found that some patients have unexpectedly low levels of natriuretic peptide hormone in clinical situations that should cause high levels of the hormone.
By Leigh MacMillan
March 9, 2021

Markers for breast cancer progression

Vanderbilt researchers clarify how a microRNA associated with triple-negative breast cancer survival inhibits cancer progression, suggesting new treatment strategies.
By Sarah E. Glass
March 4, 2021

Targeting glucagon action in diabetes

Disrupting the action of glucagon — a pancreatic hormone that works to raise blood glucose — restores functional insulin-producing cells in mouse models of type 1 diabetes and may be a promising treatment strategy.
By Leigh MacMillan
February 18, 2021

Gene variant and glucose metabolism

Genetic variation that impacts glucose- and insulin-related signaling affects responses to type 2 diabetes treatments and warrants further study.
By Leigh MacMillan
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