Department of Medicine

May 6, 2015

Neurofibromin fine-tunes bone growth

The protein neurofibromin acts as a brake in a signaling pathway that is important in bone development, Vanderbilt researchers have discovered.

By Leigh MacMillan
April 30, 2015

RNA defects in multiple sclerosis

Vanderbilt researchers have discovered that profound defects exist in the integrity of structural RNA molecules in patients with relapsing remitting multiple sclerosis.

By Leigh MacMillan
April 20, 2015

Boosting beta cells in diabetes

New findings suggest that it might be possible to treat diabetes by regenerating insulin-producing beta cells in the pancreas.

By Leigh MacMillan
April 16, 2015

Surprising finding in the kidney

TGF-beta signaling in the kidney was thought to be a target for reducing renal fibrosis, but Vanderbilt researchers report that fibrosis still occurs in the absence of TGF-beta signaling.

By Barbara O'Brien
April 6, 2015

New player in heart cell growth

Vanderbilt researchers have identified a new protein involved in heart cell growth, which could improve understanding of pathologic cardiac hypertrophy.

By Leigh MacMillan
April 3, 2015

Cancer signaling pathway blocker

Researchers at Vanderbilt University have discovered a new way to inhibit Hedgehog (Hh) signaling, an important regulatory pathway for vertebrate development – and cancer.

By VUMC News and Communications
February 25, 2015

Antibiotics with anticancer potential

A series of experimental antibiotics may be a good starting point for developing new anticancer drugs.
By Leigh MacMillan
January 28, 2015

New clue to a devastating disease

New findings suggest a previously unrecognized role for the Sox10 transcription factor in Hirschsprung’s disease, and may lead to improved diagnostic and therapeutic approaches for this disease.
By Bill Snyder
January 14, 2015

Inner ear keeps bones strong

Alterations of the vestibular system - the part of our inner ear that controls balance - may contribute to bone loss related to both aging and space travel.
By Matthew Correia
January 13, 2015

Cognitive changes in ‘standing’ syndrome

Patients with orthostatic intolerance – problems when standing – have cognitive changes, even when seated, compared to healthy individuals.
By VUMC News and Communications
January 9, 2015

Does fish oil help prevent A-fib?

Growing evidence suggests that fish oil, thought to directly prevent inflammation, oxidative stress and heart disease, may have limited clinical utility.
By VUMC News and Communications
December 18, 2014

Atrial disease and hypertension links

New findings suggest that misfolded proteins accumulate in the heart atria, particularly in patients with hypertension, and may contribute to atrial heart disease.
By Leigh MacMillan
December 17, 2014

Target for atherosclerosis therapies

A newly identified “atheroprotective” gene is a tool for exploring plaque pathophysiology and may be a good target for therapies to slow atherosclerosis progression.
By Leigh MacMillan