Department of Pharmacology

Cody Siciliano, PhD, is studying the neural substrates of memory.
September 24, 2020

Cohen Fund bolsters Siciliano’s memory research

Cody Siciliano, PhD, assistant professor of Pharmacology in the Vanderbilt University School of Medicine, has been selected to receive a one-year, $100,000 research award from the Stanley Cohen Innovation Fund to support his studies of the neural substrates of memory.

By Bill Snyder
September 3, 2020

New clue to Alzheimer’s disease

Combining studies of genetically diverse mouse populations and human data led to the identification of a gene associated with cognitive decline and brain changes in Alzheimer’s disease.

By Bill Snyder
September 3, 2020

Assembling cell power plant machinery

Tina Iverson and colleagues provide a structural view into the assembly of a protein machine essential for cellular energy production.

By Leigh MacMillan
From left, Huan Tao, MD, PhD, Sean Davies, PhD, Jiansheng Huang, PhD, and MacRae Linton, MD, led the study that identified a potential new treatment for atherosclerosis.
August 20, 2020

‘Scavenger’ molecule may point to new atherosclerosis treatment

A small-molecule “scavenger” that reduces inflammation and formation of atherosclerotic plaque in blood vessels in mice potentially could lead to a new approach for treating atherosclerosis in humans, according to researchers at Vanderbilt University Medical Center.

By Bill Snyder
July 14, 2020

New tools to study bioactive lipids

Vanderbilt researchers have identified and characterized inhibitors of an enzyme that synthesizes lipid signaling molecules with roles in energy balance, inflammation and addiction.

By Leigh MacMillan
brain and lightning
June 22, 2020

Single mutation causes seizure disorder

A single mutation in one gene can impair inhibitory signaling in the brain and cause multiple types of seizures and behavioral abnormalities.

By Leigh MacMillan
June 12, 2020

Robotic technology speeds arrhythmia gene classification

Vanderbilt University Medical Center investigators have used high-throughput robotic technology to rapidly study and classify variations in a gene linked to heart rhythm disorders and cardiac conditions.
By Leigh MacMillan
March 19, 2020

Blocking stress-induced relapse

Danny Winder and colleagues are teasing apart the actions of neurotransmitter receptors in a brain region linked to anxiety and addiction, with a goal of finding treatments for substance use disorders.
By Bill Snyder
March 4, 2020

Neurotransmitter expert Amara set for March 12 Discovery Lecture

Susan Amara, PhD, scientific director of the Intramural Research Program at the National Institute of Mental Health (NIMH) and an expert on the biology of neurotransmitter transporters, will deliver the next Flexner Discovery Lecture on Thursday, March 12.
By Bill Snyder
January 27, 2020

A new contributor to atherosclerosis

Sean Davies and colleagues are exploring lipid aldehydes produced during oxidative stress and their contribution to HDL dysfunction and atherosclerosis.
By Leigh MacMillan
December 31, 2019

Kavalali receives Humboldt Research Award

Ege T. Kavalali, PhD, professor and acting chair of the Department of Pharmacology in the Vanderbilt University School of Medicine, has been elected a recipient of a prestigious Humboldt Research Award by the Alexander von Humboldt Foundation of Germany.
By Bill Snyder
December 20, 2019

Reversing stress-related anxiety

Inhibiting COX-2 — an enzyme associated with inflammation — could provide a novel therapeutic approach for stress-related psychiatric disorders.
By VUMC News and Communications
December 17, 2019

Cell fate signaling

A newly identified protein interaction that affects cell cycle regulation may be an attractive target for cancer therapy.
By Leigh MacMillan
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