Department of Pharmacology

Cancer’s SOS

Stephen Fesik and colleagues are advancing cancer drug discovery with the characterization of small molecules that modulate RAS, an important target for anti-cancer therapies.

New way to stimulate learning?

Vagus nerve stimulation could be beneficial for treating Alzheimer’s disease and other forms of cognitive impairment, Vanderbilt research findings suggest.

Reprogramming cells for kidney repair

Using gene transfer technologies to reprogram adult human kidney cells could lead to novel therapies for chronic kidney disease.

Vanderbilt scientists report new modeling of brain signaling

The release of neurotransmitters and hormones in the body is tightly controlled by complex protein machinery embedded in cell membranes.

Gene identified that increases risk of antibiotic reaction

Researchers at Vanderbilt University Medical Center and colleagues have identified a gene that increases the risk for a severe and potentially life-threatening reaction to the commonly prescribed antibiotic vancomycin.

Modulating stress circuits

Danny Winder and colleagues demonstrate an interaction between two signaling pathways — and its impact on the activity of neurons that respond to stress.

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