Genome Research

VUMC part of major step to achieving precision medicine

An analysis of genomic data from nearly 250,000 participants in the National Institutes of Health’s All of Us Research Program has identified more than 275 million previously unreported genetic variations, nearly 4 million of which have potential health consequences.

Discovery Lecturer outlines new genome editing technique

A mere 30 months since it was first described in the online edition of Science magazine, a new genome editing technique has, by many accounts, revolutionized the study of genes and disease.

Deciphering DNA code

VU study identifies DNA changes in drug-resistant cancer cells

Vanderbilt investigators have combined next-generation sequencing technologies and bioinformatics analyses to screen for genome-wide genetic mutations associated with drug resistance in a series of lung cancer cell lines.