glioblastoma

February 15, 2022

Predicting brain cancer outcome

Red blood cell distribution width has prognostic value for many diseases, but it was not associated with overall survival in patients with glioblastoma, Vanderbilt researchers found.

By VUMC News and Communications
January 5, 2022

Drug modifies epigenome in aggressive brain tumors: study

A folic acid-like drug changed a DNA process within brain tumors of glioblastoma patients, according to results from a phase 1 clinical trial.

By Tom Wilemon
February 22, 2021

MRI view of brain tumor prognosis

In patients with glioblastoma brain tumors, features detected on MRIs at diagnosis were associated with survival, Vanderbilt Medical Center investigators found.

By Leigh MacMillan
May 3, 2016

Drug combos for glioblastoma

Vanderbilt researchers have discovered that activation of a certain signaling pathway protects brain cancers from targeted therapies, suggesting that using therapeutics that block both pathways may be a promising treatment.

By Leigh MacMillan
brain illustration
January 16, 2014

New approach may halt glioblastoma’s ability to grow

Vanderbilt University researchers have discovered a “backdoor” approach to blocking an enzyme that fuels the growth of glioblastoma, the most common and most fatal form of brain cancer.

By Bill Snyder
March 20, 2013

New drugs a good BET for brain cancer

A novel class of drugs that target “BET” proteins may have broad utility for treating genetically diverse brain tumors.

By Leigh MacMillan
February 4, 2013

Brain tumor TIP reveals new target

The protein TIP-1 appears to be a novel prognostic marker for glioblastoma and may be a good therapeutic target for disrupting tumor-driven blood vessel development.
By Leigh MacMillan
August 9, 2012

Network approach yields glioblastoma clues

MicroRNA “regulatory networks” generated at Vanderbilt aid search for biomarkers and new drugs to treat glioblastoma, the most common and lethal primary brain tumor.
By Bill Snyder