glucose

December 29, 2023

Glucose metabolism influences B cell function

Glucose metabolism influences the qualities of activated, mature B cells — white blood cells that are required for antibody-mediated immune responses, Vanderbilt researchers discovered.

By Leigh MacMillan
From left, Kimryn Rathmell, MD, PhD, Bradley Reinfeld, Matthew Madden and Jeffrey Rathmell, PhD, have discovered that immune cells — not cancer cells — are the major glucose consumers in the tumor microenvironment, upending a century-old observation.
April 7, 2021

Study revises understanding of cancer metabolism

Tumors consume glucose at high rates, but a team of Vanderbilt researchers has discovered that cancer cells themselves are not the culprit, upending models of cancer metabolism that have been developed and refined over the last 100 years.

By Leigh MacMillan
Insulin in vials
February 18, 2021

Gene variant and glucose metabolism

Genetic variation that impacts glucose- and insulin-related signaling affects responses to type 2 diabetes treatments and warrants further study.

By Leigh MacMillan
Insulin in vials
June 15, 2017

VUMC team’s discovery could lead to new diabetes treatment

By Bill Snyder
March 8, 2016

Fat hormone’s role in zebrafish

The hormone leptin regulates glucose balance, but not fat stores, in zebrafish.

By Leigh MacMillan
February 20, 2015

Tiny model of diabetes

Vanderbilt University researchers have created a zebrafish model of skeletal muscle insulin resistance that could help improve diabetes treatment.

By Bill Snyder
January 22, 2015

Beta cell link to fasting glucose

New findings explain why variation in a particular gene is the most important determinant of fasting blood glucose levels in humans.
By VUMC News and Communications
April 16, 2014

Channel drug restores glucose balance

A new compound that activates potassium channels could be used to treat disorders of glucose homeostasis.
By Bill Snyder
April 30, 2012

Better blood pressure-reducing drugs?

A newer version of an old class of blood pressure lowering drugs may offer advantages for obese patients with metabolic syndrome.
By Leigh MacMillan
March 21, 2012

Obesity turns “good” cholesterol bad

Studies offer new insights into how obesity impairs the function of HDL, the “good” cholesterol.
By Leigh MacMillan