H. Charles Manning

Blocking tumor ‘signals’ and ‘fuel’

Combining two drugs reduced colorectal cancer cell growth in vitro and in an animal model, suggesting the combination may be a promising treatment for patients.

Charles Manning, PhD, and colleagues are working to improve the effectiveness of immunotherapies earlier in treatment.

Project seeks new way to assess immunotherapy effectiveness

GE Healthcare has awarded researchers in the Vanderbilt University Institute of Imaging Science $2.5 million in funding to develop PET tracer that will determine the effectiveness of immunotherapy in patients early in their treatment course.

Grant supports novel imaging initiative to enhance cancer care

A Vanderbilt initiative to develop predictive imaging technologies that clinicians can use to better match patients with personalized care has received National Cancer Institute (NCI) funding.

VUMC researchers find a way to ‘starve’ cancer

Researchers at Vanderbilt University Medical Center (VUMC) have demonstrated for the first time that it is possible to starve a tumor and stop its growth with a newly discovered small compound that blocks uptake of the vital nutrient glutamine.

PET imaging to predict tumor response

A PET probe that detects the amino acid glutamine predicts whether tumors respond to certain targeted therapies in preclinical animal models.

Grant spurs study of novel imaging technique for COPD

Vanderbilt researchers have received an R01 grant from the National Institutes of Health to study a novel non-invasive imaging approach to detect activation of inflammatory cells in the lungs of patients with chronic obstructive pulmonary disease (COPD), a progressive lung condition that makes breathing difficult.