Henrique Serezani

C. Henrique Serezani, PhD, right, and colleagues, from left, Amondrea Blackman, Nathan Klopfenstein and Júlia Miranda Ribeiro Bazzano are studying the early events of the inflammatory response to infection.

Study details early events of inflammatory response

Vanderbilt University Medical Center investigators have identified a key molecular player in the early events of the inflammatory response to infection. The findings suggest new therapeutic possibilities for enhancing the inflammatory response to protect against pathogens and for blocking inflammation gone awry in diseases like arthritis and atherosclerosis.

Parsing diabetic skin infections

Vanderbilt researchers have discovered a role for an inflammatory mediator in diabetic skin infections, suggesting new therapeutic targets for this common complication of diabetes.

3d rendering white blood cells with red blood cells

Putting the brakes on sepsis

An enzyme called PTEN reduces inflammatory signaling and mortality in sepsis, suggesting it may be a good therapeutic target for this life-threatening complication of infection.