hospital acquired infections

Erin Green, PhD, Eric Skaar, PhD, MPH, and colleagues are studying how a certain bacterial pathogen can survive on hospital surfaces for months with no water.
May 5, 2022

VUMC team discovers how bacterial pathogen survives without water

Vanderbilt researchers are studying a bacterial pathogen that can survive on hospital surfaces — without water — for months, an ability that has helped it become a leading cause of hospital-acquired infections.

By Leigh MacMillan
September 30, 2021

Molecular imaging of C. diff infection

C. difficile — the leading cause of hospital-associated intestinal infections — induces a rapid influx of bile acids into the gut, which could provide a novel target for blocking infection.

By Leigh MacMillan
September 17, 2020

Probing pathogen antibiotic resistance

Understanding how bacteria evolve resistance to antibiotics and host stresses could guide the development of more effective antimicrobial therapeutics.

By Leigh MacMillan
January 13, 2020

Zinc uptake by a deadly pathogen

The increasingly antibiotic-resistant bacterium Acinetobacter baumannii requires zinc to cause infection, and Vanderbilt researchers have identified the zinc uptake system it uses.

By Leigh MacMillan
white pills spilling out of a prescription bottle
January 17, 2019

Pain relievers a risk for C. diff?

A link between anti-inflammatory drugs such as ibuprofen and C. diff infection suggests caution against overusing such drugs in patients at high risk for infection.

By Leigh MacMillan
June 28, 2018

New staph virulence factor

Jun. 28, 2018—The new factor, an enzyme involved in host-pathogen interactions, may be a viable target for treating staph infections.

By Leigh MacMillan
June 13, 2018

Novel infection fighter

A drug in use clinically to help make vaccines more effective may be a powerful new tool for fighting antibiotic-resistant infections.
By Meredith Jackson
October 19, 2017

Room-cleaning robots use UV radiation to zap microorganisms

Germ-killing robots are being enlisted to further safeguard Vanderbilt University Medical Center (VUMC) patients from health care-associated infections.
By Paul Govern
November 4, 2015

Detect and defend against pathogens

Understanding factors, such as the receptor TLR9, that detect and defend against pathogens may lead to therapeutic approaches that promote an effective immune response to treat infections.
By Leigh MacMillan
June 4, 2015

Study identifies C. diff toxin receptor, suggests new treatment approaches

Vanderbilt University investigators have identified a cellular receptor for a toxin from Clostridium difficile (“C. diff”) — the leading cause of hospital-acquired diarrhea in the United States.
By Leigh MacMillan
January 21, 2015

Findings do not support chlorhexidine bathing in ICUs

Vanderbilt University Medical Center researchers have found that bathing critically ill patients with disposable chlorhexidine cloths did not decrease the incidence of health care-associated infections when compared to less expensive nonantimicrobial cloths, according to a study appearing online in JAMA this week.
By Kathy Whitney
February 7, 2013

PICU reaches new milestone in fight against infections

On Jan. 10, the Pediatric Intensive Care Unit at the Monroe Carell Jr. Children’s Hospital at Vanderbilt reached impressive new territory — 365 days without a single case of central line associated blood stream infection (CLABSI), catheter associated urinary tract infection (CAUTI) or ventilator associated pneumonia (VAP).
By Paul Govern