insulin

April 16, 2014

Channel drug restores glucose balance

A new compound that activates potassium channels could be used to treat disorders of glucose homeostasis.

By Bill Snyder
Insulin in vials
April 10, 2014

Matrix remodeling and insulin resistance

The extracellular matrix that surrounds cells plays a role in the development of insulin resistance.

By Will Fry
January 29, 2014

Is healthy obesity possible?

It might be possible to generate a “metabolically healthy” state of obesity by targeting signaling pathways that improve insulin sensitivity.

By Leigh MacMillan
cells
January 13, 2014

Searching for beta cell stimulators

Vanderbilt researchers describe a new technique for identifying factors that stimulate the proliferation of pancreatic beta cells – factors that might offer therapeutic options for diabetes.

By Leigh MacMillan
Insulin in vials
October 16, 2013

Relaxin combats insulin resistance

The hormone relaxin may offer a novel approach for treating diet-induced insulin resistance.

By Leigh MacMillan
August 9, 2013

‘Yo-yo dieting’ inflames fat tissue

Gaining and losing weight during “yo-yo dieting” may contribute to an exaggerated immune response in fat tissue that increases metabolic dysfunction more than steady weight gain alone.

By Leigh MacMillan
June 6, 2013

Matrix member key to insulin resistance

A component of the extracellular matrix that surrounds cells plays a role in insulin resistance and may be a good therapeutic target.
By Leigh MacMillan
April 3, 2013

“Silent” B cells trigger autoimmunity

Immune cells that recognize self antigens (e.g. insulin), but are functionally silent, can trigger autoimmune diseases such as diabetes.
By Leigh MacMillan
February 28, 2013

Discovery Lecture explores brain’s sensitivity to insulin

Diabetes has a big impact on the brain.
By Bill Snyder
January 20, 2012

Pumping up the pancreas in pregnancy

A strain of mutant mice provide a novel model for studying glucose intolerance and gestational diabetes during pregnancy and suggest that certain molecules may be useful for therapeutic applications.
By Leigh MacMillan