A component of the extracellular matrix that surrounds cells plays a role in insulin resistance and may be a good therapeutic target.

Immune cells that recognize self antigens (e.g. insulin), but are functionally silent, can trigger autoimmune diseases such as diabetes.

Diabetes has a big impact on the brain.

A strain of mutant mice provide a novel model for studying glucose intolerance and gestational diabetes during pregnancy and suggest that certain molecules may be useful for therapeutic applications.