journal publication

Target acquired for aggressive tumor

New therapeutic target for angiosarcoma – an aggressive, highly fatal tumor of the blood vessels – identified.

Cell entry ports for cold virus

The respiratory virus HMPV uses its fusion (F) protein – which interacts with cellular receptors called integrins – to bind to and enter target cells.

HER2 may impact lung cancer therapy

A protein associated with aggressive breast cancers may also influence resistance of lung cancer to targeted therapies.

How ‘Jedi’ disposes of dead neurons

The protein Syk is essential for clearing away neuron “corpses” in the developing peripheral nervous system.

Cells with LIP eat their neighbors

A transcription factor called LIP is capable of causing one cell to consume another.

Stomach

Enzyme counters stomach acid attack

Dysfunction or loss of an “antioxidant” enzyme may lead to higher risk for esophageal cancer in patients with gastric reflux disease.

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