medulloblastoma

A brain-builder called “Shh”

New findings demonstrate a previously unappreciated role of Shh signaling activity in the proliferation of CGNPs — the presumed cell-of-origin for a subset of the malignant pediatric brain tumor medulloblastoma.

brain illustration

Roots of childhood brain tumors

Cells in the back of the developing brain can give rise to brain tumors, suggesting they may be a target for treatment.