mood disorders

Sex counts in the brain as seasons change

Photoperiod, or length of day, has sex-specific impacts on dopamine dynamics in the brain, offering insights into sex differences in neuropsychiatric disorders, Vanderbilt researchers report.

Mood and cognition after chemotherapy

Validation of cognitive complaints appears to improve mood in patients with persistent chemotherapy-cognitive impairment, Vanderbilt researchers report.

Study explores nicotine patch to treat late-life depression

Backed by nearly $5 million in funding, researchers from Vanderbilt University Medical Center are testing to see whether transdermal nicotine patches can improve mood, forgetfulness and attentiveness in adults over 60 with a diagnosis of depression.

Early detection of schizophrenia

Inhibited temperament — a tendency to respond to novelty with wariness, fear or caution — may be a risk factor for schizophrenia that could be targeted for preventative interventions.

Regulating anxiety in the brain

Two brain signaling pathways have overlapping functions in regulating anxiety, suggesting that therapeutics aimed at one or the other will impact both.

Reversing stress-induced anxiety

Augmenting the signals of natural “endocannabinoids” in the brain may be a promising approach for treating mood and anxiety disorders.