NCI

February 14, 2019

Probing H. pylori cancer protein

Understanding how a bacterial protein that influences the risk of stomach cancer is produced could guide new strategies for treatment.

By Leigh MacMillan
February 14, 2019

The yin and yang of cell signaling

Larry Marnett and colleagues have explored the role of two enzymes in metabolizing molecules associated with cell proliferation, inflammatory processes and neurological diseases.

By Sanjay Mishra
array of test tubes with pipette dropping fluid into one
January 31, 2019

Destructive ‘telegrams’ in asthma

Vanderbilt investigators have discovered that certain microRNAs — “telegram”-like signals — increase after the induction of allergic airway inflammation.

By Bill Snyder
January 17, 2019

Signals from the “conveyor belt”

Vanderbilt researchers propose that cellular signaling pathways are amplified by a “conveyor belt” mechanism that exchanges active and inactive enzymes.

By Bill Snyder
(iStock)
January 17, 2019

Building a pancreas

Vanderbilt investigators are defining the genetic programs that control the development of pancreatic beta cells — studies that could inform new cellular or regenerative therapies for diabetes.

By Leigh MacMillan
January 10, 2019

Bile acids mediate metabolic benefits of weight-loss surgery

A team of Vanderbilt investigators has pinpointed the role of bile acids and a specific signaling pathway in the positive metabolic effects of weight-loss surgery.

By Leigh MacMillan
December 13, 2018

Breast cancer-killing RIG

A compound that activates a virus-sensing receptor has potent therapeutic effects in a mouse model of breast cancer.
By Leigh MacMillan
November 29, 2018

Analyzing single-cell landscapes

Vanderbilt researchers have developed a new tool for quantifying data from single-cell studies.
By Leigh MacMillan
November 29, 2018

Green tea and diabetes

In a large population study of Chinese adults, Vanderbilt researchers found that green tea drinking increased risk of type 2 diabetes.
By Leigh MacMillan
November 15, 2018

Immunotherapies linked to specific heart complications

In the first large-scale analysis of cardiovascular complications linked to immune checkpoint inhibitors, Vanderbilt researchers have shown that heart and vessel complications include myocarditis, pericarditis, vasculitis and arrhythmias, and that they occur early in the course of treatment.
By Tom Wilemon
November 1, 2018

Team’s findings show glutamine metabolism affects T cell signaling

The cellular nutrient glutamine launches a metabolic signaling pathway that promotes the function of some immune system T cells and suppresses others, Vanderbilt researchers have discovered.
By Leigh MacMillan
October 26, 2018

Clues to bone metastases

Vanderbilt researchers are developing new approaches to study the mechanisms underlying why breast cancer cells home to bone and lie dormant, evading treatment.
By Sanjay Mishra
October 25, 2018

Studying cellular deliveries

Vanderbilt researchers have characterized the functional transfer of long RNAs between colorectal cancer cells — a form of cell-cell communication that may contribute to cancer aggressiveness.
By VUMC News and Communications
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