Vanderbilt researchers have developed a method for isolating extracellular vesicles and nanoparticles — a complex transport system involved in health and disease — which will improve biomarker discovery and the identification of therapeutic targets.

Adding blood and imaging biomarkers to a clinical prediction model could improve diagnostic accuracy for the 1.6 million lung nodules detected each year, many through expanded lung cancer screening programs.

Largest genetic study of breast cancer to date identifies 222 genetic risk loci, 137 genes and multiple signaling pathways associated with risk, providing important new insights.

Microbiome profiling of older Chinese adults showed that tea drinking changed the diversity and abundance of some bacteria in men but not women — effects that may contribute to a reduced risk of hypertension.

A Vanderbilt study found that targeting iron metabolism in immune system cells may offer a new approach for treating systemic lupus erythematosus — the most common form of the chronic autoimmune disease lupus.

Autoantibodies against the p53 tumor suppressor protein may be a novel biomarker for identifying people, especially African Americans, at high risk for lung cancer.

VUMC researchers have linked microRNAs with systemic lipid peroxidation, a discovery that could point to new therapeutic targets for a variety of diseases.