NCI

October 12, 2017

A switch for autoimmunity

Vanderbilt investigators have discovered a class of compounds that inhibit a mediator of inflammation and autoimmune disorders, and that could pave the way for development of future therapies.

By VUMC News and Communications
September 14, 2017

Acid reflux cancer link

Blocking acid reflux-induced production of reactive oxygen compounds may be a useful strategy for preventing DNA damage and decreasing the risk of esophageal cancer.

By Sanjay Mishra
Lymphocytes attacking cancer cell
August 31, 2017

Pancreatic cancer development

Elevated levels of the factor G-CSF appear to promote the development of aggressive pancreatic cancer, suggesting a new therapeutic approach for this devastating disease.

By Leigh MacMillan
August 9, 2017

Stress may switch on bone “mets”

New findings could explain the link between chronic stress and reduced survival in women diagnosed with breast cancer, and could lead to new strategies to improve treatment outcomes.

By Bill Snyder
x-ray of stomach
August 8, 2017

Early drivers of gastric cancer

Using bioinformatics approaches, Vanderbilt investigators have identified gene expression networks that are deregulated in mouse and human stomach cancers.

By Leigh MacMillan
August 3, 2017

HDAC3 role in B-cell development

The histone deacetylase HDAC3 is required for the maturation of B cells, white blood cells that produce antibodies.

By Leigh MacMillan
July 20, 2017

Drivers of breast cancer metastasis

Signaling through a complex of proteins called mTORC2 plays a role in breast cancer migration, invasion and metastasis, Vanderbilt researchers reported.
By Leigh MacMillan
June 29, 2017

Genetics of lung cancer survival

Vanderbilt investigators have conducted a first-of-its-kind genome-wide association study of lung cancer survival in African-Americans.
By Sanjay Mishra
June 19, 2017

STINGing combination for cancer

A novel immunotherapy combination induced remarkable regression of tumors in a mouse model of head and neck cancer.
By VUMC News and Communications
June 14, 2017

PET imaging to predict tumor response

A PET probe that detects the amino acid glutamine predicts whether tumors respond to certain targeted therapies in preclinical animal models.
By Leigh MacMillan
June 12, 2017

Repriming replication roadblocks

New findings shed light on how enzymes that replicate DNA skip over mutations that might cause cancer and restart DNA synthesis further away.
By Sanjay Mishra
March 30, 2017

Nanobeacon lights up colon tumors

A novel fluorescent nanobeacon can distinguish normal from diseased colon tissue, potentially offering advantages for colorectal cancer screening.
By Bill Snyder
March 17, 2017

New target for colorectal cancer

Vanderbilt investigators have discovered that activated epidermal growth factor receptor may be a target for therapies to prevent colorectal cancer development.
By VUMC News and Communications
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