NCI

July 15, 2015

Drug signaling networks

Vanderbilt investigators have developed a new algorithm to understand the networks of signaling molecules that control drug action.

By Leigh MacMillan
July 13, 2015

Hhex on cancer

A new mouse model demonstrates that the Hhex gene – which is linked to blood cancers – is critical for normal blood cell production.

By Henry H. Ong
HIV cell
June 12, 2015

New strategy to combat HIV

Inhibitors of the enzyme phospholipase D1 suppress the replication of HIV-1, Vanderbilt investigators have discovered.

By Bill Snyder
April 2, 2015

Aging insights from budding yeast

The proteins that control entry and exit from the cell nucleus influence aging, Vanderbilt researchers have discovered.

By Leigh MacMillan
February 19, 2015

‘Stretched’ cells promote cancer

Mechanical stress appears to be a critical factor in activating normal tissue-associated fibroblasts to generate cancer-associated fibroblasts.

By Leigh MacMillan
February 9, 2015

Gene profile predicts metastasis

A specific gene expression profile represents a novel, biologically relevant “signature” for identifying colon cancers with high risk of metastatic recurrence, Vanderbilt researchers have found.

By Yan Su
January 8, 2015

Enzyme affects tumor metastasis

A protein that degrades the “matrix” between cells participates in the development of lung metastases from primary breast cancer in mouse models and may be a good target for breast cancer treatment.
By VUMC News and Communications
November 11, 2014

Protein “pockets” help ID cancer genes

Vanderbilt investigators have used a computational biology approach to uncover new cancer drivers and biomarkers of anticancer drug response.
By Bill Snyder
November 6, 2014

Immune cell activity and melanoma

The activity of a certain factor in immune cells is essential for an anti-tumor response, emphasizing the need to consider the effects of anti-cancer therapies on immune cells.
By VUMC News and Communications
October 29, 2014

Key to prostate cancer resistance

A combination of two types of therapy may be more effective in treating castration-resistant prostate cancer.
By VUMC News and Communications
October 28, 2014

Improving breast cancer chemo by testing tumors in a dish

A team of biomedical engineers has developed a new "tumor-in-a-dish" technology that promises to improve the effectiveness of chemotherapy.
By VUMC News and Communications
October 14, 2014

Neuronal culprit in genetic disease

A particular neuronal cell population is involved in the pathogenesis of a rare neurological disorder, Vanderbilt researchers have discovered.
By Leigh MacMillan
September 25, 2014

A path to sarcoidosis treatment

Vanderbilt investigators identify a new therapeutic target for the inflammatory lung disease sarcoidosis.
By VUMC News and Communications
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