NCI

April 2, 2015

Aging insights from budding yeast

The proteins that control entry and exit from the cell nucleus influence aging, Vanderbilt researchers have discovered.

By Leigh MacMillan
February 19, 2015

‘Stretched’ cells promote cancer

Mechanical stress appears to be a critical factor in activating normal tissue-associated fibroblasts to generate cancer-associated fibroblasts.

By Leigh MacMillan
February 9, 2015

Gene profile predicts metastasis

A specific gene expression profile represents a novel, biologically relevant “signature” for identifying colon cancers with high risk of metastatic recurrence, Vanderbilt researchers have found.

By Yan Su
January 8, 2015

Enzyme affects tumor metastasis

A protein that degrades the “matrix” between cells participates in the development of lung metastases from primary breast cancer in mouse models and may be a good target for breast cancer treatment.

By Daren Diiorio
November 11, 2014

Protein “pockets” help ID cancer genes

Vanderbilt investigators have used a computational biology approach to uncover new cancer drivers and biomarkers of anticancer drug response.

By Bill Snyder
November 6, 2014

Immune cell activity and melanoma

The activity of a certain factor in immune cells is essential for an anti-tumor response, emphasizing the need to consider the effects of anti-cancer therapies on immune cells.

By VUMC News and Communications
October 29, 2014

Key to prostate cancer resistance

A combination of two types of therapy may be more effective in treating castration-resistant prostate cancer.
By VUMC News and Communications
October 28, 2014

Improving breast cancer chemo by testing tumors in a dish

A team of biomedical engineers has developed a new "tumor-in-a-dish" technology that promises to improve the effectiveness of chemotherapy.
By VUMC News and Communications
October 14, 2014

Neuronal culprit in genetic disease

A particular neuronal cell population is involved in the pathogenesis of a rare neurological disorder, Vanderbilt researchers have discovered.
By Leigh MacMillan
September 25, 2014

A path to sarcoidosis treatment

Vanderbilt investigators identify a new therapeutic target for the inflammatory lung disease sarcoidosis.
By VUMC News and Communications
August 28, 2014

Limiting breast cancer metastasis

Vanderbilt researchers have identified a new target for blocking breast cancer metastasis.
By Brandon Turner
August 14, 2014

Growth factor blockade targets breast tumors

Inhibition of BMP growth factor signaling reduces breast tumor burden and metastasis.
By VUMC News and Communications
August 6, 2014

Low selenium and lung cancer

Vanderbilt researchers have found that selenium deficiency may contribute to the racial disparity in lung cancer incidence.
By Yan Su