NCI Archive — Page 19 of 26

Dense circular scatter plot composed of many multicolored dots, with several larger colored points distributed throughout.
August 5, 2014

Drug discovery clues in network map

Vanderbilt investigators have constructed a network map that could guide the development of new targeted cancer therapies.

Close-up of a person wearing a pink polo shirt with a pink awareness ribbon pinned to the chest.
July 31, 2014

New target for breast cancer therapy

The protein MTBP is overexpressed in an aggressive type of breast cancer, and it regulates another protein implicated in many cancer types, suggesting that it may be a good target for new therapeutics.

Fluorescence microscopy image showing a network of neurons with branching red and green processes against a black background.
July 18, 2014

Neural receptor for reovirus

A newly identified receptor allows mammalian reovirus to infect neurons, shedding light on factors important for viral encephalitis.

Stylized green molecular model beside blue DNA double-helix structures.
May 23, 2014

Repair protein’s DNA recognition motif

Insights into the workings of DNA damage response proteins such as SMARCAL1 could suggest new ways to improve genome integrity and prevent cancer.

May 22, 2014

Cellular forces aid tumor invasion

The contractile machinery inside tumor cells increases invasive properties, suggesting it might be a good target to inhibit cancer cell spread.

Glowing white DNA double helix over a blue background with circuit-board patterns and light effects.
May 9, 2014

Bypassing DNA damage

Studies of a human polymerase that replicates DNA have provided a complete kinetic and structural framework for understanding how the enzyme accurately bypasses DNA damage.