NHLBI

Low oxygen and antibody responses

Mark Boothby and colleagues are exploring the factors that contribute to antibody production and quality, which are key to our defense against pathogens and response to vaccines.

Cardiac dysfunction in DMD

The protein MMP7 is elevated in blood from patients with Duchenne muscular dystrophy who have cardiac dysfunction, suggesting that it may be a biomarker for heart disease severity.

Drug interaction causes hypotension

A muscle relaxing-drug and inhibitors of the metabolic enzyme CYP1A2 interact to cause severely low blood pressure and should not be co-prescribed, Vanderbilt investigators caution.

Unraveling endocytosis

New discoveries by Jason MacGurn and colleagues further understanding of the complex machinery that cells use take up substances from outside the cell.

Cell death pathway implicated in bone marrow failure

Vanderbilt investigators have linked a specific form of programmed cell death to myelodysplastic syndrome, a type of bone marrow failure.

Parsing diabetic skin infections

Vanderbilt researchers have discovered a role for an inflammatory mediator in diabetic skin infections, suggesting new therapeutic targets for this common complication of diabetes.

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