Vanderbilt researchers have discovered that the protein CRADD counteracts inflammatory injury to endothelial cells, which could assist the development of new therapies for inflammatory vascular disorders.

Importin alpha 5, a member of a family of proteins that “shuttle” other proteins into the nucleus, is a potential new target for drugs to treat inflammatory diseases.

The protein SARM appears to protect cells from inflammation-driven death by stabilizing the nuclear laminin scaffold.

Even relatively low levels of in utero alcohol exposure impact fetal brain development, and the effects last into adulthood, study finds.

Therapeutic agents focusing on the brain region involved in stress-induced relapse may be effective in preventing relapse in patients with alcohol use disorders.