NIDDK

February 8, 2016

Building intestinal brush borders

Studies of the molecular complex that helps build specialized cellular surfaces could shed light on the mechanisms underlying a genetic deaf-blindness syndrome accompanied by intestinal disease.

By Leigh MacMillan
December 14, 2015

DISSECTing cell signaling networks

Vanderbilt researchers have developed a new method to study cell signaling networks at single-cell resolution.

By Leigh MacMillan
green traffic light
December 3, 2015

Microtubules act as cellular ‘rheostat’ to control insulin secretion

Microtubules — cellular “highways” that deliver cargo to the cell membrane for secretion — have a surprising role in pancreatic beta cells. Instead of facilitating glucose-stimulated insulin secretion, they limit it, a team of Vanderbilt investigators reported recently in Developmental Cell.

By Leigh MacMillan
Insulin in vials
November 18, 2015

Fighting type 2 diabetes with FGF1

The growth factor FGF1 induces the growth of new insulin-producing beta cells and may help treat type 2 diabetes.

By VUMC News and Communications
November 12, 2015

Immune system a must for kidney repair

A signaling protein that is essential for recovery from acute kidney injury works by increasing the population of tissue-repairing immune cells.

By Lorena Infante
November 4, 2015

Detect and defend against pathogens

Understanding factors, such as the receptor TLR9, that detect and defend against pathogens may lead to therapeutic approaches that promote an effective immune response to treat infections.

By Leigh MacMillan
October 29, 2015

Inflammation, obesity and diabetes

Vanderbilt study adds to the mounting role for inflammatory signaling in obesity.
By Leigh MacMillan
October 1, 2015

Tolerating a transplant

A new genetic model has generated new strategies for promoting tolerance to transplants – and improving long-term transplant outcomes – in the background of autoimmune disease.
By Leigh MacMillan
September 9, 2015

How to build a basement

Understanding the action of a certain enzyme will shed light on basement membrane function, and on disorders ranging from diabetic kidney disease to cancer.
By Sanjay Mishra
September 4, 2015

Vitamin C protects blood vessel lining

Dietary vitamin C may maintain healthy blood vessels in patients with inflammatory diseases.
By Leigh MacMillan
August 12, 2015

Origins of neuroblastoma

Vanderbilt researchers are exploring how neuroblastoma tumors begin and progress, knowledge that could provide new treatments for this pediatric cancer.
By Leigh MacMillan
August 6, 2015

Stomach cancer cues

Vanderbilt scientists have discovered a new molecular mechanism that promotes stomach cancer development, findings that could provide new opportunities for treatment.
By VUMC News and Communications
July 23, 2015

Study explores protein’s role in inflammation-associated cancer

An antioxidant protein may protect against colon cancer that develops in patients with inflammatory bowel disease, suggesting new strategies for reducing colon cancer risk in these patients.
By Leigh MacMillan
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