NIEHS

model of DNA double helix

Faulty building blocks in DNA

An enzyme that builds DNA is able to insert the wrong building blocks, which could generate mutations.

How the cell makes morphine

Vanderbilt investigators have discovered how mammals, including humans, produce the painkiller morphine.

Study explores protein’s role in inflammation-associated cancer

An antioxidant protein may protect against colon cancer that develops in patients with inflammatory bowel disease, suggesting new strategies for reducing colon cancer risk in these patients.

Copper toxicity and Parkinson’s

A genetic predisposition to Parkinson’s disease makes neurons more vulnerable to the toxicity of heavy metals such as copper.

New tools to probe manganese biology

Vanderbilt researchers have developed tools to probe the role of the essential metal manganese in neurons, and which offer a started point for developing therapeutic agents for manganese-related neurological disorders.

Dioxin, fathers and preterm birth

Exposure of male mice to the pollutant dioxin causes preterm birth across multiple generations, suggesting that efforts to prevent preterm birth should include pre-conception interventions for dads.

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