NIGMS

Mapping brain membrane proteins

New mass spectrometry imaging methods will enable studies of the distribution and identification of membrane proteins directly within tissues.

Tumor factor spurs blood vessel growth

A newly identified factor regulates blood vessel growth in colorectal tumors and could be a promising target for cancer therapies.

Oxidative stress in autism

A biomarker for oxidative stress is elevated in patients with both autism spectrum disorder and gastrointestinal dysfunction, suggesting opportunities for individualized approaches to clinical care.

Motor protein revs up cell division

A motor protein that helps drive cell division may be a promising new target for cancer therapeutics.

Visualizing data on network ‘maps’

The new web application NetGestalt will allow investigators to simultaneously visualize different types of data for the same gene – such as mutation, expression and modification.

Disease linked to cell traffic jams

Diseases associated with mutations and changes in expression of the protein caveolin may result from faulty trafficking of the protein to the cell surface.

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