NIGMS

Structural studies reveal a new framework for understanding a central player in DNA processing.

Understanding how the main receptor for light interacts with other signaling molecules may inform new pharmaceutical development.

It may be possible to fight hospital-acquired pathogens like Acinetobacter baumannii by targeting the bacterium’s need for the nutrient metal zinc.

The machinery that builds the characteristic shape of epithelial cells suppresses breast cancer formation and metastasis in a mouse model.

Study adds evidence for infectious agents’ role in sarcoidosis, an inflammatory condition that can lead to respiratory failure and death.

The structural architecture of the reovirus attachment protein is required for efficient reovirus infection of host cells.

Vanderbilt investigators have identified how two key components of cancer's invasive "switch" — the series of signaling events that turn on a tumor cell’s invasive behavior — work together.