NIGMS

Antibacterial protein’s molecular workings revealed

Vanderbilt investigators report new insights to the workings of calprotectin, an immune system protein that “starves” bacterial pathogens of the metal nutrients they require.

Cure in sight for kissing bug’s bite

It’s possible to cure Chagas disease – a deadly tropical infection transmitted by “kissing bugs” – in a mouse model.

New view of DNA processing ‘hub’

Structural studies reveal a new framework for understanding a central player in DNA processing.

Seeing light receptor’s interactions

Understanding how the main receptor for light interacts with other signaling molecules may inform new pharmaceutical development.

Zinc: a new antibiotic target?

It may be possible to fight hospital-acquired pathogens like Acinetobacter baumannii by targeting the bacterium’s need for the nutrient metal zinc.

Polarity protein suppresses tumor growth, invasion

The machinery that builds the characteristic shape of epithelial cells suppresses breast cancer formation and metastasis in a mouse model.

1 17 18 19 20 21 22