NIH

Applications accepted for S10 instrumentation grants from NIH

The NIH S10 program encourages applications from groups of NIH-supported investigators to purchase or upgrade a single item of expensive, specialized, commercially available instrumentation or an integrated system.

Team identifies ‘switch’ involved in DNA replication  

DNA replication is an extraordinarily complex multi-step process that makes copies of the body’s genetic blueprint. It is necessary for growth and essential to life. Now researchers at the California Institute of Technology (Caltech) and Vanderbilt University have found evidence that one of those steps may involve the telephone-like transmission of electrical signals regulated by a chemical “switch.”

Researchers chart new informatics path in tracking disease risk

In a study in Circulation: Cardiovascular Genetics, Vanderbilt University’s Jonathan Mosley, M.D., Ph.D., and colleagues use genetic correlation to hitch together two unrelated sets of data, one from a longstanding epidemiological cohort and the other from electronic health records.

A target to heal tiny lungs

The protein beta-catenin may be a good target for therapies to treat lung disease that is a common complication of preterm birth.

tiny petri dishes with wires in them

Organ-on-a-chip mimics heart’s biomechanical properties

Scientists at Vanderbilt University have created a three-dimensional organ-on-a-chip that can mimic the heart’s amazing biomechanical properties in order to study cardiac disease, develop heart drugs.

Improving therapies for GI tumors

A signaling protein overexpressed in upper gastrointestinal cancers is an attractive therapeutic target.

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