NIH

Improving vaccine formulations

The compound MPLA is an attractive vaccine component, designed to elicit a robust immune response.

Illustration of human intestinal tract

Colorectal cancer clues

Although cancers arising from different areas of the large intestine are heterogeneous, they appear to use similar important tumorigenic pathways.

Digestive Disease Research Center lands major grant

The Vanderbilt Digestive Disease Research Center (VDDRC) celebrates its 15th anniversary this year with a third consecutive five-year renewal of its federal research grant.

Close-up of a woolen knitted texture (blue)

Surprising finding by VU team sheds light on fibrotic disease

Integrins are membrane proteins made up of combinations of different “alpha” and “beta” subunits that enable cells throughout the body to interact with their surroundings.

Hacker typing on a laptop

Metastatic pancreatic cancer ‘reprograms’ for malignancy

Metastatic pancreatic cancer — cancer that has spread from the pancreas to other tissues and is responsible for most patient deaths — changes its metabolism and is “reprogrammed” for optimal malignancy, according to new findings reported Jan. 16 in Nature Genetics.

color-enhanced cross section of tumor tissue

Softening tumor tissue could aid cancer treatments

Tumors cause the intracellular material surrounding them to stiffen. Softening this protective layer could make existing cancer treatments more effective, according to new research.

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