NIH

Close-up of a woolen knitted texture (blue)
January 19, 2017

Surprising finding by VU team sheds light on fibrotic disease

Integrins are membrane proteins made up of combinations of different “alpha” and “beta” subunits that enable cells throughout the body to interact with their surroundings.

By Bill Snyder
Hacker typing on a laptop
January 19, 2017

Metastatic pancreatic cancer ‘reprograms’ for malignancy

Metastatic pancreatic cancer — cancer that has spread from the pancreas to other tissues and is responsible for most patient deaths — changes its metabolism and is “reprogrammed” for optimal malignancy, according to new findings reported Jan. 16 in Nature Genetics.

By Leigh MacMillan
color-enhanced cross section of tumor tissue
January 16, 2017

Softening tumor tissue could aid cancer treatments

Tumors cause the intracellular material surrounding them to stiffen. Softening this protective layer could make existing cancer treatments more effective, according to new research.

By VUMC News and Communications
January 6, 2017

Midgut neuroendocrine tumor prognosis

Vanderbilt investigators recommend that the presence of tumor deposits in the abdomen be included when staging midgut neuroendocrine tumors.

By Leigh MacMillan
Clinical and translational research at Vanderbilt will be funded over the next five years, thanks to a $46 million renewal grant from the National Center for Advancing Translational Sciences. (Mary Donaldson/Vanderbilt)
January 5, 2017

Department of Medicine’s NIH funding swells

Vanderbilt University School of Medicine has long been recognized as a national leader in biomedical research. Nowhere is this more evident than in the school’s Department of Medicine, which, during the 2016 federal fiscal year that ended Sept. 30, broke another record.

By Bill Snyder
December 27, 2016

Investigational new drug for Alzheimer’s scheduled for first study in humans

Vanderbilt University scientists have received notification from the U.S. Food and Drug Administration that testing in humans may proceed for an investigational new drug for Alzheimer’s disease after more than 10 years of research by scientists at Vanderbilt University and Vanderbilt University Medical Center.

By Craig Boerner
December 22, 2016

Discovery sheds new light on Angelman, Prader-Willi syndromes

A mutation associated with epilepsy and autism also is responsible for a “pale eye” trait in two rare genetic disorders, Angelman syndrome and Prader-Willi syndrome, neuroscientists at Vanderbilt University Medical Center reported this week.
By Meredith Jackson
December 15, 2016

New clues emerge in rare form of childhood epilepsy

Researchers at Vanderbilt University Medical Center (VUMC) are one step closer to understanding what causes early-onset epileptic encephalopathy, a rare form of childhood epilepsy that is difficult to treat and has poor developmental outcomes.
By Bill Snyder
December 12, 2016

Single-cell analysis of solid tumors

A new method will make it possible to study solid tumors and healthy tissues using mass cytometry.
By Heather McCartney
December 9, 2016

Protecting the blood-brain barrier

Vanderbilt investigators have discovered how a promising cancer immunotherapy causes brain swelling, findings that could lead to ways to protect brain function while fighting cancers.
By Sanjay Mishra
December 8, 2016

Making human beta cells reproduce

A new method developed at Vanderbilt will speed the search for potential therapeutics for diabetes: compounds that stimulate the replication of insulin-producing beta cells.
By VUMC News and Communications
December 8, 2016

Plasmin prevents muscle ‘hardening’ after injury: study

Vanderbilt researchers have made the surprising discovery that the protease plasmin, known for its clot-busting role in the blood, protects soft tissue from turning to bone after severe injuries and certain orthopaedic surgeries.
By Leigh MacMillan
December 6, 2016

Blood-brain barrier on a chip sheds new light on “silent killer”

A new microfluidic device containing human cells that faithfully mimics the behavior of the blood-brain barrier is providing new insights into brain inflammation, the silent killer.
By VUMC News and Communications
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