NIH

tug-of-rope pair
November 3, 2016

VUMC investigators find pathogens work together to infect host

Pseudomonas aeruginosa and Staphylococcus aureus — two pathogens that frequently co-infect the lungs of patients with cystic fibrosis — appear to cooperate with each other, Vanderbilt investigators have discovered. When pseudomonas is starved for metal by the host, it shuts down the production of factors that would normally kill staph, promoting a co-infection.

By Leigh MacMillan
x-ray of stomach
November 3, 2016

A DARPP role in gastric cancer

Vanderbilt researchers have discovered a link between Helicobacter pylori infection, inflammation and gastric cancer that could suggest new anti-cancer therapies.

By Sanjay Mishra
November 3, 2016

Cellular interactions found to contribute to lung fibrosis

Specific interactions between inflammatory cells and epithelial cells contribute to lung fibrosis, according to a study published last week in JCI Insight fromVanderbilt’s Lisa Young, M.D., associate professor of Pediatrics and Medicine and Cell and Developmental Biology, and colleagues.

By Kathy Whitney
glowing brain cell
October 27, 2016

Bioluminescent sensor causes brain cells to glow in the dark

A team of Vanderbilt scientists have genetically modified luciferase, the enzyme that produces bioluminescence, so that it acts as an optical sensor that records activity in brain cells.

By VUMC News and Communications
October 27, 2016

Study tracks makeup of VUMC collaborative care teams

At Vanderbilt University Medical Center (VUMC) there are about 486 distinct operational units involved in inpatient care and evaluation.

By Paul Govern
October 26, 2016

Single-cell study of tumor samples

A new method for analyzing cells in fixed biopsy tissues from patients by guide personalized treatment strategies for cancer.

By Leigh MacMillan
October 24, 2016

Sleep issues in children with diabetes

Lengthening sleep duration and reducing sleep disturbances in children with type 1 diabetes may improve diabetes outcomes and reduce parental stress.
By Leigh MacMillan
October 21, 2016

DNA damage response protein

Vanderbilt researchers have determined that a previously uncharacterized protein responds to DNA replication stress and has an essential role in maintaining the integrity of the genome.
By Bill Snyder
October 20, 2016

Preparing for a return of pox

To prepare for the potential of a smallpox return, Vanderbilt researchers are isolating and studying naturally occurring antibodies from the blood of previously infected or immunized people.
By Bill Snyder
October 20, 2016

Study finds natural compound extends lifespan of worms

A compound found in buckwheat seeds extends the lifespan of worms, Vanderbilt investigators have discovered.
By Leigh MacMillan
October 20, 2016

Research sheds light on how RSV wards off potential vaccines

Respiratory syncytial virus (RSV) is the major cause of life-threatening viral pneumonia in infants worldwide, yet despite repeated efforts, scientists have been unable to develop an effective vaccine against it.
By Bill Snyder
October 13, 2016

EGF receptor found to regulate macrophage inflammation in gut

Researchers at Vanderbilt University School of Medicine have uncovered a link between epidermal growth factor receptor (EGFR) signaling and the inflammatory response to bacterial infection in the gastrointestinal tract.
By Bill Snyder
October 13, 2016

Grant spurs research on how nerves guide organ function

Michelle Southard-Smith, Ph.D., associate professor of Medicine in the Vanderbilt University School of Medicine, has won a major award from the National Institutes of Health (NIH) to support her research on how nerves control organ function.
By Bill Snyder
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