NIH

Illustration of human intestinal tract

$5.2M NIH grant bolsters colorectal cancer research

Robert Coffey Jr., M.D., Ingram Professor of Cancer Research at Vanderbilt University, has received a five-year, $5.2 million grant from the National Institutes of Health (NIH) to study the role of extracellular RNA (ex-RNA) in colorectal cancer.

Oxidative stress in autism

A biomarker for oxidative stress is elevated in patients with both autism spectrum disorder and gastrointestinal dysfunction, suggesting opportunities for individualized approaches to clinical care.

Noninvasive test detects stomach bug

A noninvasive test can be used to identify the presence of Helicobacter pylori and evaluate its virulence, which will be useful in areas with high rates of H. pylori-associated gastric cancer.

‘Yo-yo dieting’ inflames fat tissue

Gaining and losing weight during “yo-yo dieting” may contribute to an exaggerated immune response in fat tissue that increases metabolic dysfunction more than steady weight gain alone.

Nuclear shield against cell death

The protein SARM appears to protect cells from inflammation-driven death by stabilizing the nuclear laminin scaffold.

Older woman shopping

Cognitive complaints, Alzheimer’s risk studied

A study of cognitive complaints in older adults showed that memory concerns from both the patient and an informant was most predictive of converting to Alzheimer’s disease or dementia within three years.

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