oxidative damage

March 7, 2024

Study details metabolism of biomarkers for oxidative stress

Factors other than oxidative stress can modify the levels of biomarkers called isoprostanes that are commonly used in both experimental and clinical research, suggesting that additional standards need to be developed.

By Leigh MacMillan
January 6, 2023

MicroRNAs linked to lipid damage

VUMC researchers have linked microRNAs with systemic lipid peroxidation, a discovery that could point to new therapeutic targets for a variety of diseases.

By Sarah E. Glass
February 12, 2018

Protecting transplanted lungs

Acetaminophen may offer a simple treatment to prevent tissue injury following lung transplant, Vanderbilt researchers have discovered.

By Leigh MacMillan
Buckwheat seeds on wooden spoon in closeup
October 20, 2016

Study finds natural compound extends lifespan of worms

A compound found in buckwheat seeds extends the lifespan of worms, Vanderbilt investigators have discovered.

By Leigh MacMillan
May 9, 2014

Bypassing DNA damage

Studies of a human polymerase that replicates DNA have provided a complete kinetic and structural framework for understanding how the enzyme accurately bypasses DNA damage.

By VUMC News and Communications
March 28, 2013

Acetaminophen: protective in sepsis?

In critically ill patients with sepsis, plasma hemoglobin may be a new indicator of disease severity – and a potential target for treatment with acetaminophen.

By Leigh MacMillan
September 11, 2012

Enzyme counters stomach acid attack

Dysfunction or loss of an “antioxidant” enzyme may lead to higher risk for esophageal cancer in patients with gastric reflux disease.
By VUMC News and Communications