PET

From left, Kimryn Rathmell, MD, PhD, Bradley Reinfeld, Matthew Madden and Jeffrey Rathmell, PhD, have discovered that immune cells — not cancer cells — are the major glucose consumers in the tumor microenvironment, upending a century-old observation.

Study revises understanding of cancer metabolism

Tumors consume glucose at high rates, but a team of Vanderbilt researchers has discovered that cancer cells themselves are not the culprit, upending models of cancer metabolism that have been developed and refined over the last 100 years.

Potential probe for early ovarian cancer

Larry Marnett and colleagues have developed what may become the first agent for targeted PET imaging of cancer tissues, such as ovarian cancer, that express high levels of the COX-1 enzyme.

PET imaging to predict tumor response

A PET probe that detects the amino acid glutamine predicts whether tumors respond to certain targeted therapies in preclinical animal models.

Superior scan for tumors

Imaging with a compound that binds to neuroendocrine cells is a safer and more effective way to detect rare neuroendocrine tumors.

Grant to spur study of ‘brown fat’s’ metabolic mysteries

Vanderbilt researchers have received a $2.15 million grant to study the amount and activity of “brown fat” in adults, with the aim of understanding its role in metabolic disease and identifying new therapeutic targets.

Brain and doorway concept

Minds wide open: Neuroscience at Vanderbilt

Vanderbilt University has emerged as one of the nation’s leading academic centers in neuroscience.