PNAS

January 23, 2014

Human and Helicobacter co-evolution

By VUMC News and Communications
December 19, 2013

Ancient chemical bond may aid cancer therapy: study

A chemical bond discovered by Vanderbilt University scientists that is essential for animal life and which hastened the “dawn of the animal kingdom” could lead to new therapies for cancer and other diseases.

By Bill Snyder
November 8, 2013

Defusing ‘C. diff’ infection

By Leigh MacMillan
October 10, 2013

Probing mutant EGF receptor regulation

Understanding the regulation of mutant EGF receptors commonly found in lung cancers could lead to new targeted therapies.

By Leigh MacMillan
April 25, 2013

Food variety drives overeating in mouse model of obesity syndrome

Dietary variety – not high-fat or sugary foods – appears to stimulate overeating in a mouse model of an inherited obesity syndrome.

By Bill Snyder
February 21, 2013

Antibacterial protein’s molecular workings revealed

Vanderbilt investigators report new insights to the workings of calprotectin, an immune system protein that “starves” bacterial pathogens of the metal nutrients they require.

By Leigh MacMillan
January 18, 2013

Seeing light receptor’s interactions

Understanding how the main receptor for light interacts with other signaling molecules may inform new pharmaceutical development.
By Leigh MacMillan
October 23, 2012

Stomach bug alters tumor suppressor

The stomach bug Helicobacter pylori increases forms of a protein that promote tumor development, perhaps explaining how it elevates risk for gastric cancer.
By Leigh MacMillan
October 18, 2012

Setting traps to probe gene function

A new method for creating genetic mutations that can be activated at certain times or in specific tissues will enable studies to probe gene function.
By Leigh MacMillan
July 3, 2012

Receptor’s role in nutrition brain circuitry

New findings point to brain circuitry that communicates about the body’s nutritional status and regulates how nutrients are mobilized.
By Leigh MacMillan
April 27, 2012

Dengue antibodies give vaccine leads

New information may help speed development of a vaccine or treatment for dengue fever.
By VUMC News and Communications
March 2, 2012

‘Detangler’ binds, bends and cuts DNA

New details on the DNA-cutting activity of topoisomerase II, a target of anti-cancer drugs, could lead to better chemotherapeutic agents.
By Leigh MacMillan
January 23, 2012

Alcohol’s molecular mediators

Therapeutic agents focusing on the brain region involved in stress-induced relapse may be effective in preventing relapse in patients with alcohol use disorders.
By Leigh MacMillan