premature birth

In this 3D projected still image from a precision cut lung slice, alveolar epithelial cells are labeled green. All other cells are seen in purple.

Vanderbilt researchers envision the potential to grow new lungs

Using a four-dimensional microscope that allows them to watch a tissue putting itself together, researchers at Vanderbilt University Medical Center have achieved a rare feat in science — they have shattered a long-standing dogma about how the lung develops.

From left, Nicholas Negretti, PhD, Jonathan Kropski, MD, John Benjamin, MD, MPH, Jennifer Sucre, MD, and Erin Plosa, MD, led the research team that created a single-cell “atlas” of lung development. (photo by Erin O. Smith)

“Atlas” of lung development may aid efforts to heal premature lungs

Researchers at Vanderbilt University Medical Center have constructed a single-cell “atlas” of lung development that tracks multiple cell types over time.

Tailoring treatment for heart defect

By defining the clinical and genetic factors that predict treatment response, Vanderbilt investigators aim to personalize therapy for a common heart complication in preterm infants.

Fetal membranes and microbial threats

Understanding how cells communicate in the membranes surrounding the developing fetus could suggest new strategies for preventing infections, premature birth and adverse pregnancy outcomes.

The nursing staff agreed to let LeBar hold newborn daughter in a technique called “ventral skin-to-skin contact,” which has been shown to improve premature infants’ health, both short- and long-term.

My Southern Health: The benefit of skin-to-skin contact for infants

Ventral skin-to-skin contact has been shown to improve premature infants’ health, both short- and long-term. The baby is undressed or unwrapped and placed against the mother’s bare skin, nestled against her chest. A cozier name for this method of holding a new baby is “kangaroo care.”

Therapies to prevent preterm birth

Vanderbilt researchers have developed a high-throughput assay that will aid in identifying new compounds to treat preterm labor or postpartum bleeding.